AGE-RELATED CHANGES IN SLEEP-DEPENDENT EMOTIONAL MEMORY
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Memory bias
研究概览
简要总结
Memory influences emotional well being. Research has shown that having a negative emotional bias contributes to both emotion dysregulation and depression. Conversely, reactivating positive memories has been shown to reduce stress and symptoms of depression. In young adults, sleep is widely implicated in emotional processing, including consolidation of emotional memories. Evidence suggests that aging is associated with changes in emotion, including a positive memory bias and enhanced emotional well-being. These changes have been termed the "age-related positivity effect." However, the influence of sleep on these measures has not been investigated in healthy older individuals. The objective of this research is to understand the role of sleep in emotional memory consolidation and emotional well-being across adulthood. We hypothesize that sleep contributes to the age-related positivity effect in memory and affect. Our alternative hypothesis is that age-related decreases in sleep are responsible for reduced emotional memory processing over healthy aging.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-30 or 50-80 years of age
- •Have no history of a sleep disorder
- •Have no history of neurological disease or injury
- •Have no history of psychiatric illness (anxiety or mood disorder, schizophrenia, etc.)
- •No history of chemotherapy
- •Not be taking medications which effect sleep
- •Habitually sleep more than 6 or more hours per night
- •Be able to walk freely and independently
- •Have normal to corrected-to-normal vision
排除标准
- 未提供
结局指标
主要结局
Memory bias
时间窗: 12 hr delay between encoding and recognition test
Corrected recognition of positive versus negative pictures
次要结局
未报告次要终点
研究者
Rebecca Spencer
Associate Professor
University of Massachusetts, Amherst
