Prevalence of Periodontal Disease Among Egyptian Patients With Multiple Sclerosis S: A Cross Sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 293
- 试验地点
- 1
- 主要终点
- Prevalence of periodontal disease as assessed by clinical periodontal parameters ( clinical attachment loss )within the study population.
研究概览
简要总结
The goal of this observational study is to explore the association between multiple sclerosis and periodontal disease in a sample of Egyptian population
The main question it aims to answer is:
• Is there an association between MS and periodontal disease Participants already diagnosed with multiple sclerosis. A conventional oral examination will be held on a dental unit, filling charts and patients' acceptance to participate in the survey.
详细描述
Periodontal disease is a chronic inflammatory condition leading to progressive destruction of the supporting structures of the teeth. Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that may share common inflammatory pathways with periodontal disease. Recent evidence suggests that systemic inflammation may influence the severity and progression of both conditions.
This study will recruit participants already diagnosed with MS and assess their periodontal status using standard clinical parameters, including clinical attachment loss (CAL), probing pocket depth, and bleeding on probing measured at six sites per tooth using a periodontal probe. Data will be collected through a conventional oral examination in a dental unit, and results will be compared to evaluate the prevalence and potential association between MS and periodontal disease within this population.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with MS
- •Adult patients ≥ 18 years old.
- •Patients providing an informed consent
排除标准
- •Periodontal therapy within the last 3 months.
- •Having surgical therapy or undergoing orthodontic treatment
- •Pregnant females
- •Patients with systemic condition know to impact the periodontal condition other than MS (eg. Diabetes Mellitus)
- •Patients having more than 5 lost teeth
结局指标
主要结局
Prevalence of periodontal disease as assessed by clinical periodontal parameters ( clinical attachment loss )within the study population.
时间窗: Baseline
CAL will be measured as the distance from the cementoenamel junction (CEJ) to the base of the periodontal pocket using a periodontal probe at six sites per tooth. Mean CAL will be calculated for each participant to assess periodontal tissue destruction.
次要结局
未报告次要终点
研究者
Hend Mohamed wageh Eltonsy
Principal investigator
Cairo University