Prevalence of cirrhotic cardiomyopathy and its implications in patients undergoing living donor liver transplantation - A prospective observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
研究概览
简要总结
Liver transplant is the definitive treatment for patients with end stage liver disease
Due to altered physiological condition patients with cirrhosis develop a phenomenon called cirrhotic cardiomyopathy
Cirrhotic cardiomyopathy is defined as cardiac dysfunction in patients with cirrhosis in the absence of prior cardiac disease
In 2019 the cirrhotic cardiomyopathy consortium criteria reviewed electrophysiological changes in cirrhotic cardiomyopathy and discussed their clinical relevance and potential treatment strategies
Systolic dysfunction like left ventricular ejection fraction less than or equal to fifty percentage or absolute global longitudinal strain less than 18
Advanced diastolic dysfunction with three or more like
Septal e velocity of less than 7
E by e prime ratio of more than or equal to 15
Left atrial volume index of more than 34
Tricuspid regurgitation velocity of more than 2.8
Along with these other condition like any changes in electrocardiography or electromechanical uncoupling or serum biomarkers
All these will be analysed by trans thoracic echocardiography in pre anaesthesia checkup and during post operative period
Cardiac changes will be analysed and any cardiac events will be noted
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •All patients between 18 to 65 years of age who are undergoing living donor liver transplant surgery at our institution.
排除标准
- •Patient refusal Diagnosed with known cardiac disease.
- •ischaemic heart disease, valvular or structural heart disease Acute liver failure Chronic kidney disease.
研究者
Nisha Maharu M G
Institute
