Clinical Intuition for PRedicting Evolution in Sepsis in the Emergency Department - CIPRES-ED Study
试验速览
- 阶段
- 不适用
- 入组人数
- 692
- 试验地点
- 1
- 主要终点
- Compare emergency physicians' clinical intuition versus qSOFA score for prediction of 30-day mortality in patients with suspected infection
研究概览
简要总结
Sepsis is a syndrome involving infection and an abnormal systemic inflammatory response in the infected organism, resulting in organ dysfunction and possibly death. It is a major cause of hospital mortality. A large proportion of sepsis diagnoses are made in emergency departments. Early diagnosis and appropriate treatment have been shown to reduce mortality from this disease.
In a context of limited resources, it is therefore important to be able to quickly stratify patients presenting to the emergency department with a suspected infection into those who require rapid and intensive management because they are at risk of developing sepsis and septic shock and those who can be managed conventionally The objective of this study is to compare the clinical intuition of emergency room physicians and nurses with the qSOFA score to predict the clinical course of patients presenting to the emergency room with potential sepsis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients presenting to one of the participating emergency departments with suspected infection, defined as the presence of at least one of these parameters:
- •Temperature ≥ 38°C ou < 36°C measured in the emergency room Chills (in the emergency room or on recent history)
- •No objection to participation in the study
排除标准
- •Minor patient (<18 years)
- •Patient under guardianship or other protective measure
- •Patient unable to understand research information
- •Patient refusing the use of their data for research purposes
结局指标
主要结局
Compare emergency physicians' clinical intuition versus qSOFA score for prediction of 30-day mortality in patients with suspected infection
时间窗: 1 month after inclusion
We compare the area under the ROC curve of each test (Emergency physicians' clinical intuition versus qSOFA score) to predict 30-day mortality in patients with suspected infection
次要结局
- Compare emergency physicians' clinical intuition versus qSOFA score for prediction of 72 hours mortality in patients with suspected infection(72 hours after inclusion)