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临床试验/NCT05018715
NCT05018715Unknown不适用

Research on the Diagnostic Value of Machine Learning Model Based on Clinical Data in Patients With Coronary Heart Disease

Xiang Ma1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2021年8月22日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
600
试验地点
1
主要终点
make a definite diagnosis of CHD

研究概览

简要总结

Based on the clinical data of patients, a machine learning model for coronary heart disease diagnosis was established to evaluate whether the model could improve the accuracy of coronary heart disease diagnosis, and to evaluate its authenticity, reliability and benefits.

详细描述

A total of 300 patients with CHD WHO were hospitalized in the First Affiliated Hospital of Xinjiang Medical University from August 2021 to February 2022 were selected, all of whom met the DIAGNOSTIC criteria of CHD formulated by the World Health Organization (WHO) and excluded diseases such as highly severe valvular disease and congenital heart disease.A total of 300 healthy subjects from the First Affiliated Hospital of Xinjiang Medical University during the same period were selected as controls.Observation indicators included: Clinical indicators collected included: General conditions: gender, age, medical history;Blood biochemical indexes, such as blood routine, liver function, kidney function, blood lipid, blood glucose, myocardial markers, electrolyte, serum creatinine concentration, body mass index, BNP and other indicators;Related tests such as ELECTROcardiogram, holter electrocardiogram, cardiac ultrasound (left atrial diameter, ascending aorta, ventricular septal thickness, left posterior wall thickness, right ventricular diameter, ejection fraction, abnormal ventricular wall motion, evidence of infarction or ischemia, valve abnormality, congenital heart disease, etc.);Signs include: audio data of heart sounds in nine parts of precardiac area;Medication status.All blood biochemical indexes and examinations were completed in the laboratory department and ultrasound department of our hospital, and the physical signs were completed in the ward.The results of coronary angiography, pre-hospital and post-hospital echocardiography and other related data were recorded.Machine learning model was constructed based on clinical data to assist diagnosis of patients with coronary heart disease

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who meet the diagnostic criteria for CHD set by the World Health Organization

排除标准

  • Exclude serious valvular disease, congenital heart disease, respiratory system and other diseases.

结局指标

主要结局

make a definite diagnosis of CHD

时间窗: 2021-2023

Based on the patient's typical angina pectoris symptoms, combined with the patient's age and coronary heart disease risk factors, and excluding other causes of angina pectoris, a preliminary diagnosis can be established. Coronary CTA, coronary angiography and other examinations find direct evidence of coronary artery stenosis, which can confirm the diagnosis

次要结局

未报告次要终点

研究者

发起方
Xiang Ma
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Xiang Ma

professor

First Affiliated Hospital of Xinjiang Medical University

研究点 (1)

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