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临床试验/CTRI/2025/01/079722
CTRI/2025/01/079722尚未招募不适用

A CLINICO-COMPARATIVE STUDY OF ABHADI CURNA AND ASVAGANDHAMULA CURNA PLUS ATIBALAMULA CURNA IN THE PATIENTS OF JANU SANDHIGATAVATA (KNEE OSTEO ARTHRITIS)

J s ayurveda mahavidyalaya1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年2月3日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
To find out the effect of Abhadi churna in compare to Ashwagandhamula churna plus atibalamula churna by observing the changes in VAS and WOMAC SCALE before and after treatment in the patients of Janusandhigata vata

研究概览

简要总结

Sandhigatavata occurs when vitiated vata lodges in sandhi Caraka explained sandhigatavata with symptoms of sotha(swelling) vatapurna druti sparsha(on palpation revealed as air filled bag) and Akunchan Prasaranayo vedana(pain on flexion and extension of joints) Susruta also mentioned sula and sotha in this disease leading to the restricted movement of involved joint Madhav nidan adds Aatopa(crepitus on joints) On the basis of above characteristics Janusandhigata vata can be correlated with knee osteoarthritis (OA) OA is defined as chronic joint disorder with deterioration of articular cartilage and bone at joint margin called osteophytes and capsular fibrosis It can affect many joints but most commonly affects the knee, hip and spine. Registered patients will be randomized in two groups by using the block randomization methods and from them one group will be given Abhadi churna and another group will be given Ashwagandhamula churna plus atibalamula churna and the effect of these will be observed by recording changes in VAS and WOMAC SCALE and Kellgren Lawrence system after treatment

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
40.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • • Patients fulfilling the ayurvedic as well as modern criteria of diagnosis of jānu sandhigatavāta (osteoarthritis of knee joint).
  • • Patients with signs and symptoms of knee joint osteoarthritis.
  • • Patients between age group of 40-80 years of both genders will be selected.
  • • Patients with diabetes mellitus (PP2BS less than 300 mg per dl) and Hypertension(moderate) along with jānu sandhigatavāta will also be included.

排除标准

  • • Female patients having pregnancy or lactating period.
  • • Patient with associated disease which affects the outcomes or completion of the treatment i.e., osteoporosis, hyperthyroidism or hypothyroidism, cancer, tuberculosis, heart diseases, rheumatoid arthritis, psoriatic arthritis, kidney disorders and liver disorders.
  • • Patient having past traumatic history and complete loss of articular cartilage.
  • • Patients who have taken medication of corticosteroids within last 3 months and/or NSAIDs or any antibiotic medicines within last 7 days.
  • • Patient who has history of previously joint replacement.
  • • Patients with any previous anatomical deformity.

结局指标

主要结局

To find out the effect of Abhadi churna in compare to Ashwagandhamula churna plus atibalamula churna by observing the changes in VAS and WOMAC SCALE before and after treatment in the patients of Janusandhigata vata

时间窗: 2 weeks and 4 weeks

次要结局

  • To find out the effect of Abhadi churna in compare to Ashwagandhamula churna plus atibalamula churn by observing the changes in kellegren Lawrence system in the patients of janusandhigata vata (Knee osteoarthritis)(4 weeks)

研究者

发起方
J s ayurveda mahavidyalaya
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Pinaben V Dalshaniya

J S Ayurveda Mahavidyalaya

研究点 (1)

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