Coeliac Artery Release or Sham Operation - CARoSO

Medisch Spectrum Twente0 个研究点目标入组 70 人开始时间: 待定最近更新: 2024年4月9日

适应症

试验速览

暂无简介。

•1. Patients with a consensus diagnosis of MALS based on a multidisciplinary
•discussion (vascular surgeon, MDL
•physician, radiologist). The multidisciplinary discussion will be performed in
•two seperate multidisciplinary teams (MST and EMC)
•o Typical complaints: post-prandial pain and at least one of the following:
•dietary modification, unexplained weight loss,
•unexplained diarrhea.
•o Eccentric stenosis of >=70% of the AC at the medial arcuatum ligament,
•demonstrated by two imaging techniques
•(duplex, DSA, MRA or CTA), including at least an inspiration and expiration CTA
•or MRA with 1mm sections. (Definition
•percent stenosis according to ECST 1998 formula: % stenosis = (1 - [diameter at
•the site of stenosis/estimated
•original diameter at the site of the stenosis]) x 100).
•o Ultrasound or CT or MR abdomen without other more common abnormalities.
•o Gastroscopy-duodenoscopy without abnormalities, unless appropriate for
•mucosal ischemia.
•o Age >/=18 years.

•1. Patient not suitable for endoscopic AC release (e.g. previous surgery in the
•operating area).
•2. Pregnancy.
•3. Previous (endovascular) intervention of the visceral arteries.
•4. A significant stenosis in the superior or in the inferior mesenteric artery.

发起方