Investigating the Efficacy of Cognitive Behavioral Therapy in Patients With Substance Use Disorder and Comorbid ADHD. A Randomized Controlled Trial With Cognitive Behavioral Therapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 184
- 试验地点
- 1
- 主要终点
- self reported ADHD symptoms
研究概览
简要总结
The purpose of this study is to determine if cognitive behavioral therapy is effective in treating ADHD symptoms in patients with substance use disorders and comorbid ADHD.
详细描述
Attention Deficit Hyperactivity Disorder(ADHD) is an important comorbid condition in patients with substance use disorders (SUD). The prevalence of ADHD in patients with SUD is estimated 23%, and ADHD is associated with an untoward prognosis of SUD. However, adequate treatment programs for patients with ADHD and SUD are not available. Results of medication trials for patients with ADHD and SUD are disappointing, and cognitive behavioral therapy (CBT) has not yet been investigated in this population. In patients with ADHD without comorbid SUD, the results of CBT in randomized trials are positive. The purpose of this study is to investigate if CBT is effective in treating ADHD symptoms in patients with ADHD and SUD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •substance use disorder
- •able to comply with study activities
排除标准
- •severe neurological or psychiatric diseases (for example Parkinson, dementia, psychosis, bipolar depression) which require medication
- •unable to read or write Dutch language
研究组 & 干预措施
standard addiction treatment
10 sessions of standard addiction treatment. No ADHD treatment.
addiction treatment and ADHD treatment
10 sessions cognitive behavioral therapy on addiction treatment combined with 5 sessions on ADHD treatment.
干预措施: cognitive behavioral therapy for treating ADHD symptoms (Behavioral)
结局指标
主要结局
self reported ADHD symptoms
时间窗: 6 months
Dutch self report list of ADHD symptoms by Kooij and Buitelaar
次要结局
- TIC-P(6 months)
- Stroop task(6 months)
- Beck Anxiety Inventory(6 months)
- Time Line Follow Back method(6 months)
- EQ-5(6 months)
- urine checks(6 months)
- BART task(6 months)
- Beck depression inventory(6 months)
- Tower of London task(6 months)