Effects of Peripheral and Cerebral Electrical Stimulation on Maximal Isometric Strength of Knee Extensors
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Isometric quadriceps strength
研究概览
简要总结
Quadriceps muscle strength is a key goal to be achieved in rehabilitation protocols for a variety of musculoskeletal conditions. Both cerebral and peripheral electrical stimulations can modulate motor brain areas involved in motor functions and has the potential to optimize muscle capacity. However, their effects on quadriceps function are lacking.
This study aims to investigate the effects of transcranial direct current stimulation (tDCS) and peripheral electrical stimulation (PES) on quadriceps strength in healthy subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy subjects with no complaints of pain, discomfort in the musculoskeletal system.
排除标准
- •Musculoskeletal or neurological disorder
- •Under medication
研究组 & 干预措施
Cerebral stimulation
Active transcranial direct current stimulation
tDCS: 20 minutes, 2mA, primary motor cortex anode (contralateral to the dominant lower limb) and supraorbital cathode (ipsilateral to the dominant lower limb).
干预措施: Cerebral stimulation (Device)
Combined stimulation 1
Active peripheral electrical stimulation (PES_sensorial) combined with active transcranial direct current stimulation
tDCS: 20 minutes, 2mA, primary motor cortex anode (contralateral to the lesion) and supraorbital cathode (ipsilateral to the lesion).
PES_sensorial: 20 minutes, 10Hz (frequency), 100µs (pulse duration), intensity at sensorial level.
干预措施: Cerebral stimulation (Device)
Combined stimulation 1
Active peripheral electrical stimulation (PES_sensorial) combined with active transcranial direct current stimulation
tDCS: 20 minutes, 2mA, primary motor cortex anode (contralateral to the lesion) and supraorbital cathode (ipsilateral to the lesion).
PES_sensorial: 20 minutes, 10Hz (frequency), 100µs (pulse duration), intensity at sensorial level.
干预措施: Peripheral stimulation (Device)
Peripheral stimulation
Active peripheral electrical stimulation (PES_motor).
PES: 15 minutes, 30Hz (frequency), 100µs (pulse duration), intensity at motor level.
干预措施: Peripheral stimulation (Device)
Combined stimulation 2
Active sensorial peripheral electrical stimulation (PES_sensorial) combined with active motor peripheral electrical stimulation (PES_motor)
PES_sensorial: 20 minutes, 10Hz (frequency), 100µs (pulse duration), intensity at sensorial level
PES_motor: 15 minutes, 30Hz (frequency), 100µs (pulse duration), intensity at motor level.
干预措施: Cerebral stimulation (Device)
Combined stimulation 2
Active sensorial peripheral electrical stimulation (PES_sensorial) combined with active motor peripheral electrical stimulation (PES_motor)
PES_sensorial: 20 minutes, 10Hz (frequency), 100µs (pulse duration), intensity at sensorial level
PES_motor: 15 minutes, 30Hz (frequency), 100µs (pulse duration), intensity at motor level.
干预措施: Peripheral stimulation (Device)
结局指标
主要结局
Isometric quadriceps strength
时间窗: Pre and Post-test (immediately after tDCS)
Maximal isometric voluntary contraction (Kgf)
次要结局
- Isometric quadriceps strength(10 minutes post-stimulation)
研究者
Fuad Ahmad Hazime
Assistant Professor - Physical Therapy Department
Universidade Federal do Piauí