Study of the Reversibility of Vigilance Dysfunction at 6 Months of Continuous Positive Airways Pressure (CPAP) in Patients With Obstructive Sleep
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 23
- 试验地点
- 1
- 主要终点
- Study of the reversibility of vigilance disorders on the number of omissions in the subtest visual vigilance of the TAP
研究概览
简要总结
It is a monocentric prospective pilot study in Poitiers University Hospital, specifically analyzing the vigilance disorders in the Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and their reversibility after 6 months of Continuous positive airways pressure (CPAP).
All subjects were administered a test of vigilance (Test of Attentional Performance) both before and after the 6 months of CPAP.
The main objective is the study of the reversibility of alertness disorders on the number of omissions in the subtest visual vigilance of the TAP ( (Test of Attentional Performance) at 6 months of CPAP in the OSAHS in patients with a memory complaint.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 69 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 20-70 years
- •Memory disorders without memory problems in episodic memory
- •Presence of polysomnography of a obstructive sleep apnea/hypopnea syndrome (OSAHS) requiring Continuous positive airways pressure
- •Moderate OSAHS (Apnea Hypopnea Index ≥ 15 / hour with arousals ≥ 10)
- •Severe OSAHS (Apnea Hypopnea Index ≥ 30 / h)
排除标准
- •Age <20 years or ≥ 70 years
- •Neurodegenerative disease (Alzheimer's disease, Parkinson's disease)
- •Dysthyroidism
- •Severe depression, schizophrenia, bipolar disorder
- •Treatment with an effect on cognition: hypnotics, sedative
- •Chronic Obstructive Pulmonary Disease
- •Chronic alcoholism, other addictions
- •Contraindications to Magnetic Resonance Imaging
- •Refusal of equipment
研究组 & 干预措施
tests of attentional performance
干预措施: tests of attentional performance (Diagnostic Test)
结局指标
主要结局
Study of the reversibility of vigilance disorders on the number of omissions in the subtest visual vigilance of the TAP
时间窗: After 6 months of continuous positive airways pressure in the OSAHS patient
Reversibility of vigilance disorders on the number of omissions in the subtest visual vigilance of the TAP
次要结局
未报告次要终点