Multimodal Data-assisted Primary Screening for Allergic Rhinitis Based on Voice Recognition and Face
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,500
- 试验地点
- 1
- 主要终点
- Allergen Test Results
研究概览
简要总结
Collect facial images and voice and audio of patients with rhinitis in the department of otolaryngology, and collect the examination results of patients with rhinitis who have received electronic fiber nasopharyngoscopy. Skin prick test to a standard panel of aeroallergens or by using the ImmunoCAP Phadiatop test for detecting immunoglobulin E antibodies against various common inhalant allergenswere detected, and a prediction model for the type of rhinitis was finally established.
详细描述
The incidence of allergic rhinitis is high and the progression of the disease is serious, but public awareness of the disease is limited. Mistaking allergic rhinitis for the common cold or other respiratory illnesses and purchasing non-specific medications for its treatment not only delays proper diagnosis and treatment, but may also lead to further aggravation of the disease and complications. Such omission, misdiagnosis and mistreatment of allergic rhinitis not only affects the management and control of the disease, but may also result in unnecessary wastage of healthcare resources and increased treatment costs.
In this study, the investigators propose to capture face photographs and audio files of rhinitis patients coming to the otolaryngology clinic using a work cell phone to determine whether the patients are allergic or non-allergic rhinitis by using an allergy detection test. The face photos, audio files and basic clinical information were multimodally fused to construct a prediction model, and the effectiveness of the model was evaluated.
Ultimately, it is expected that the predictive model can simply identify and screen for allergic rhinitis, improve public awareness and understanding of allergic rhinitis, and take proper treatment measures.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 8 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects understood the purpose and procedure of the trial and signed an informed consent form, and voluntarily participated in this study;
- •Subjects were initially clinically diagnosed with chronic rhinitis;
- •Subjects were aged 8-80 years old, limited to Chinese nationality, and were able to perform basic examinations and cooperate with face photography and voice collection.
排除标准
- •Those who received systemic immunotherapy, used systemic or local glucocorticoids as well as leukotriene receptor antagonists within one month;
- •Those who suffer from immune system diseases, autoimmune diseases, allergic diseases or allergies and have a history of food allergy;
- •Other serious systemic diseases, such as active tuberculosis, rheumatic heart disease, congenital heart disease, arthritis, nephritis, hypertension, psychosis, dermatitis, epilepsy and so on;
- •Women during lactation and pregnancy;
- •History of upper respiratory tract infection or more serious infectious diseases within three months;
- •Those who are currently participating in another clinical study or have participated in another clinical study within 90 days;
- •Other patients who, in the judgment of the clinician, are not suitable for inclusion in the study.
结局指标
主要结局
Allergen Test Results
时间窗: 30 minutes
Atopic status was evaluated by skin prick test to a standard panel of aeroallergens or by using the ImmunoCAP Phadiatop test (Phadia, Uppsala, Sweden) for detecting immunoglobulin E antibodies against various common inhalant allergens. Allergic rhinitis was diagnosed in patients with a positive skin prick or positive blood IgE.
次要结局
未报告次要终点
研究者
Zheng Liu
professor
Huazhong University of Science and Technology