Comparing anti-hypertensive combination therapy of fixed dose losartan and hydrochlorothiazide(HCTZ) versus angiotensin receptor blocker(ARB) and calcium channel blocker(CCB) on hypertensive patients whose blood pressures don't lower enough,effect and influence of metabolic system trial. - Effects of Losartan and diUretics Combination therapy on Intensive blood pressure control and DiAbetic Tolerance in East-Saitama(ELUCIDATE)

Hypertension and Metabolism Study group in East Saitama0 个研究点目标入组 300 人开始时间: 2009年2月6日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1)Patients with uncontrolled diabetes (HbA1c more than 9.0%) 2) Patients with secondary hypertension 3)Patients who have stroke, AMI and/or other critical vascular complications that required hospitalization within 24 weeks prior to the intervention 4)Patients with liver dysfunction [GPT(ALT) over three times the normal value] 5)Patients with renal failure (serum creatinine more than 2.0 mg/dL) 6)Patients with uncontrolled hyperuricemia (more than 9.0mg/dL) 7)Patients with cardiac insufficiency (more than NYHA grade III) 8) Patients with severe malignant cancer or other unfavorable prognostic factors 9)Pregnant or possible pregnant women 10)Patients with a history of hypersensitivity to ingredients of losartan potassium or hydrochlorothiazide 11)Patients with a history of hypersensitivity to thiazide or thiazide-like diuretics 12)Patients who are considered not eligible for the study by the attending doctor due to medical reasons

发起方

Hypertension and Metabolism Study group in East Saitama