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临床试验/ACTRN12618001658202
ACTRN12618001658202招募中3 期

Intraoperative Lignocaine Infusions: development of an optimised infusion dosing regimen for obese patients

RBWH Anaesthetic Department0 个研究点目标入组 30 人开始时间: 2018年10月8日最近更新:
适应症

试验速览

阶段
3 期
状态
招募中
发起方
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Non-randomised trial
主要目的
Treatment
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 90 Years(—)
性别
All

入选标准

  • Patients scheduled for elective laparoscopic abdominal surgery
  • Surgical duration expected to be of at least 90 minutes duration
  • Patients of a range of BMIs according to the WHO definitions - 10 patients with a BMI of < 35kg/m2, 10 patients with a BMI of 35-40kg/m2 and 10 patients with a BMI > 40kg/m2
  • Informed consent by patient or legally authorised representative to participate in study and to store specimens for immediate and future analysis.

排除标准

  • Known or suspected allergy to study drug (lignocaine)
  • Acute or chronic renal disease (eGFR < 60)
  • Acute or chronic liver disease
  • Congestive cardiac failure
  • Cardiac conduction abnormalities
  • History of seizure disorder
  • Known vascular disease of the upper limb (e.g. Raynauds disease), or other contraindication to arterial catheterisation

研究者

发起方
RBWH Anaesthetic Department

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