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临床试验/NCT07750782
NCT07750782进行中(未招募)不适用

Environmental and Geographic Patterns of Occupational Injuries: A Population-Based Retrospective Study

Sergio Gabriel Susmallian1 个研究点 分布在 1 个国家目标入组 350,000 人开始时间: 2020年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
350,000
试验地点
1
主要终点
Occurrence of Recognized Occupational Injury During Case Versus Matched Control Periods

研究概览

简要总结

This study will determine whether extreme ambient temperatures increase the incidence and severity of occupational injuries in Israel, and we request Helsinki Committee approval to conduct the analysis using de-identified National Insurance and historical meteorological data, with a waiver of informed consent. The project will link the date, time, and geographic location of recognized occupational accidents with corresponding historical temperature and humidity measurements. The study is retrospective, observational, and involves no direct contact with participants, no intervention, and no alteration of medical care or benefit eligibility.

详细描述

Occupational injuries represent an important source of preventable morbidity, permanent disability, loss of employment, and economic burden. Rising temperatures and increasingly frequent heatwaves may impair concentration, coordination, judgment, reaction time, hydration, and physical endurance, particularly among workers in construction, agriculture, transportation, manufacturing, and other outdoor or physically demanding occupations. However, the national relationship between ambient heat and work-related injury in Israel has not been adequately quantified. Without reliable population-level evidence, employers, occupational-health authorities, and policymakers cannot identify temperature thresholds at which preventive measures should be intensified or determine which workers and industries are at greatest risk.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Individuals aged 18 years or older with an occupational injury recognized by the National Insurance Institute.
  • Occupational injury occurring between January 1, 2020, and December 31,
  • Injury occurring at the workplace, during occupational travel, or while commuting to or from work.
  • Valid injury date and geographic information sufficient to assign the accident to one of the seven predefined geographic-climatic regions and the nearest representative meteorological station.
  • Meteorological measurements available for the injury period and eligible matched control periods.
  • For time-specific analyses, a valid recorded accident time permitting linkage to the closest preceding three-hour meteorological observation.

排除标准

  • Occupational diseases, repetitive-exposure conditions, or gradual-onset disorders without a clearly defined accident date.
  • Rejected, withdrawn, or unconfirmed occupational-injury claims.
  • Missing or invalid accident date or geographic information preventing linkage with meteorological data.
  • Accidents occurring outside the predefined geographic-climatic regions or beyond the prespecified maximum distance from an eligible meteorological station.
  • Duplicate or administratively repeated records referring to the same occupational-injury event.
  • Injury events for which no eligible matched control periods or corresponding meteorological measurements are available.
  • Individuals younger than 18 years.

研究组 & 干预措施

Northern valleys and inland north

Occupational injuries occurring in the northern valleys and inland northern region will be assigned to this geographic-climatic division according to the location of the workplace or accident. Meteorological exposure will be determined using data from the nearest representative monitoring station, including Dafna, Tavor Kadoorie, or Nazareth. This region is characterized by inland climatic conditions with substantial seasonal variation in temperature and humidity. Accident occurrence and severity will be evaluated in relation to temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.

干预措施: Ambient Weather Exposure (Other)

Northern Mediterranean coast

Occupational injuries occurring along the northern Mediterranean coastal region will be assigned to this geographic-climatic division according to the location of the workplace or accident. Meteorological exposure will be determined using data from the Haifa Technion monitoring station or the nearest available representative station. This region is characterized by a Mediterranean coastal climate, with relatively high humidity, moderate winter temperatures, warm summers, and frequent sea-breeze effects. Accident occurrence and severity will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.

干预措施: Ambient Weather Exposure (Other)

Central Mediterranean coast

Occupational injuries occurring within the central Mediterranean coastal region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Tel Aviv Coast monitoring station or the nearest available representative station. This region is characterized by a warm Mediterranean climate, relatively high humidity, mild winters, hot summers, and frequent sea-breeze effects. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.

干预措施: Ambient Weather Exposure (Other)

Southern Mediterranean coast

Occupational injuries occurring within the southern Mediterranean coastal region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Ashqelon Port monitoring station or the nearest available representative station. This region is characterized by a warm coastal Mediterranean climate, relatively high humidity, mild winters, hot summers, and frequent sea-breeze effects. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.

干预措施: Ambient Weather Exposure (Other)

Central highlands

Occupational injuries occurring within the central highlands region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Jerusalem Centre monitoring station or the nearest available representative station. This region is characterized by higher elevation, lower average humidity than the coastal areas, greater day-night temperature variation, cooler winters, and warm, dry summers. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.

干预措施: Ambient Weather Exposure (Other)

Negev desert

Occupational injuries occurring within the Negev desert region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Avdat monitoring station or the nearest available representative station. This region is characterized by an arid desert climate, very low relative humidity, intense solar exposure, high daytime temperatures, substantial day-night temperature variation, and limited rainfall. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.

干预措施: Ambient Weather Exposure (Other)

Dead Sea and extreme arid region

Occupational injuries occurring within the Dead Sea and extreme arid region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Massada monitoring station or the nearest available representative station. This region is characterized by very low elevation, an extremely hot and arid climate, low annual rainfall, intense solar radiation, prolonged periods of extreme heat, and substantial seasonal temperature variation. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, extreme heat, extreme cold, and other predefined environmental indicators. Wind speed will be analyzed when reliable measurements are available.

干预措施: Ambient Weather Exposure (Other)

结局指标

主要结局

Occurrence of Recognized Occupational Injury During Case Versus Matched Control Periods

时间窗: At the index injury date and matched control dates, January 1, 2020-December 31, 2024.

The number of accepted occupational-injury events occurring during predefined case periods will be evaluated in relation to ambient temperature, relative humidity, and wind speed obtained from the nearest representative meteorological station. Each injury period will be compared with control periods matched by geographic-climatic region, calendar year and month, day of the week, and three-hour time interval. The association between environmental exposure and occupational-injury occurrence will be estimated using time-stratified case-crossover analysis with conditional logistic regression.

次要结局

未报告次要终点

研究者

发起方
Sergio Gabriel Susmallian
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Sergio Gabriel Susmallian

Medicine doctor

Assuta Medical Center

研究点 (1)

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