ISRCTN48675191已完成未知
Epidermal growth factor enema versus mesalazine enema for the treatment of mild-to-moderate active left-sided ulcerative colitis
niversity Hospitals of Leicester NHS Trust (UK)0 个研究点目标入组 50 人开始时间: 2006年9月13日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Males and females aged above 18 with a definite diagnosis of UC or proctitis
- •2. Mild-to-moderate disease activity with a UC Disease Activity Index (UC-DAI) score between three and eight
排除标准
- •1. Patients with infectious colitis
- •2. Colonic inflammation extending proximal to the left colon (i.e. beyond the splenic flexure on sigmoidoscopic examination)
- •3. Patients receiving oral maintenance therapy with a total daily dose of more than 3 g of mesalazine within 30 days prior to study entry
- •4. Use of any immunosuppressive agent within 90 days prior to the study
- •5. Intake of corticosteroids (orally or rectally) within seven days prior to entry
- •6. Chronic use of non-steroidal anti-inflammatory drugs in seven days prior to inclusion (chronic use defined as drug intake for a minimum of seven consecutive days)
- •7. Presence of severe renal/hepatic impairment, malignant disease and allergies to salicylates
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