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临床试验/NCT02046018
NCT02046018已完成不适用

Healthy Child Uganda: Can Village Health Volunteers Trained in Integrated Community Case Management of Childhood Illness Improve Access to Care for Africa's Most Vulnerable Children?

Healthy Child Uganda0 个研究点目标入组 5,000 人开始时间: 2009年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
5,000
主要终点
Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for presumed pneumonia.

研究概览

简要总结

In Sub-Saharan Africa (SSA), many children die from diarrhoea, acute respiratory illness (ARI) and malaria, despite well- recognized, inexpensive and highly effective treatments, since health access and human resources are limited. Healthy Child Uganda (HCU) is a Ugandan-Canadian partnership that since 2003, has developed, implemented and evaluated a Village Health Volunteer (VHV) program in 175 rural villages. Volunteers, selected by peers, provide health education and refer sick children. Volunteer retention (94%) and significant decreases in child deaths are remarkable. Now, HCU wonders whether VHV scope can extend to provide treatment for sick children using Oral Rehydration Salts (ORS)/Zinc, antibiotics, and antimalarials. Use of lay providers in this capacity, called integrated community case management (iCCM), has been proposed as a potential inexpensive solution to SSA's human health resource crisis.

PRIMARY QUESTION: In rural southwest Uganda, can iCCM provided by lay volunteers, improve the proportion of children with diarrhoea receiving ORS/Zn, ARI receiving antibiotics, and fever/malaria receiving antimalarials? Secondary study questions consider VHV capacity to prescribe appropriate drug, dose, duration; iCCM acceptance by family, and VHV; VHV retention/motivation; program cost. Selected VHV will be iCCM trained then receive treatments for distribution. Qualitative and quantitative methods including household surveys, and focus groups will consider pre/post intervention differences and differences in control and intervention populations. A research short course and micro research grants (~ $3000 to multidisciplinary groups pursuing relevant questions) will promote health system evaluation capacity. Lessons learned are critical as SSA countries move forward in planning for increased iCCM programming.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
— 至 59 Months(Child)
性别
All
接受健康志愿者
是

入选标准

  • •Children under five (< or =59 months)

排除标准

  • •Children over five years (> 59 Months)

研究组 & 干预措施

ICCM delivered by VHT

Active Comparator

Health Outcomes in Communities where VHT's were trained in ICCM and given drugs.

干预措施: ICCM delivered by VHT (Other)

ICCM delivered by VHT with cell phone

Active Comparator

Health Outcomes in communities with VHT's who were trained in ICCM and given cell phones

干预措施: ICCM delivered by VHT (Other)

ICCM delivered by VHT with cell phone

Active Comparator

Health Outcomes in communities with VHT's who were trained in ICCM and given cell phones

干预措施: ICCM delivered by VHT with Cell Phone (Other)

Health outcomes in communities with no ICCM

Active Comparator

Health outcomes in communities with VHT's who were not trained in ICCM

干预措施: No intervention (Other)

结局指标

主要结局

Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for presumed pneumonia.

时间窗: March 2013 - November 2014 (8 months)

Children diagnosed by a Community Health Worker with presumed pneumonia (fast breathing and cough) treated with Amoxicillin.

Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for diarrhea

时间窗: March 2013 - November 2014 (8 months)

Children diagnosed with diarrhea will be treated with ORS and zinc.

Percentage of change in number of children under five in intervention area who receive Integrated Community Case Management Treatment from a Community Health Worker for fever.

时间窗: March 2013 - November 2014 (8 months)

Children diagnosed with fever are presumed to have malaria, as per government treatment guidelines, and are treated with Coartem.

次要结局

未报告次要终点

研究者

发起方
Healthy Child Uganda
申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Jenn Brenner

Clinical Associate Professor

Healthy Child Uganda

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