EXecution of Trans-Esophagus Echo Cardiogram in CardioPulmonary Resuscitation for Patients With Out-of-hospital Cardiac Arrest
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 132
- 试验地点
- 2
- 主要终点
- Rate of sustained return of spontaneous circulation (ROSC)
研究概览
简要总结
The purpose of this single center, randomized clinical control trial is to determine that changing chest compression site during cardiopulmonary resuscitation according to the examination of the TEE could increase the level of end-tidal CO2, which represents the quality of cardiopulmonary resuscitation, or not in adult patients with non-traumatic out-of-hospital cardiac arrest while comparing to those who don't receive examination of transesophageal echocardiography during cardiopulmonary resuscitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
盲法说明
This is an open label study
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 20 years-old
- •Out-of-hospital cardiac arrest
排除标准
- •Obvious signs of death appears, such as separation of head and body, rigor mortis, livor mortis, cankered corpse......etc.
- •Family members clearly express the willing of do not attempt resuscitation or patients who have registered advance care planning not to attempt resuscitation.
- •Patients not suitable for transesophageal ultrasound, such as patients with esophageal tumor, those whose probe cannot be placed......etc.
- •Received Extracorporeal CPR.
- •Achieving sustained ROSC before ED arrival
结局指标
主要结局
Rate of sustained return of spontaneous circulation (ROSC)
时间窗: 20 minutes after ROSC
successful restoration and maintenance of a patient's heartbeat and blood circulation after undergoing cardiopulmonary resuscitation (CPR) for at least 20 minutes
次要结局
- Rate of any return of spontaneous circulation(1 minutes after ROSC)
- Rate of survival to ICU admission(48 hours after ROSC)
- Rate of survival to discharge(6 months after ROSC)
- Rate of discharge with favorable neurological outcomes(6 months after ROSC)
- end-tidal carbon dioxide (EtCO2)(During resuscitation)