In adults with methicillin resistant staphylococcus aureus (MRSA) bacteraemia, does the combination of vancomycin plus flucloxacillin lead to a faster resolution of bacteraemia than does vancomycin alone?

In summary, our study provides an encouraging signal that the combination of vancomycin with an anti-staphylococcal ß-lactam may be useful for the treatment of MRSA bacteremia. This pilot randomized controlled trial (RCT) adds considerably to the growing literature from in vitro laboratory, in vivo animal, and retrospective clinical studies, and provides the impetus for future clinical trials involving objective clinically relevant endpoints