跳至主要内容
临床试验/NCT07455786
NCT07455786招募中不适用

Modified Trabeculectomy for Management of Early Failure of Combined Phaco With GATT or With Goinopuncture

Assiut University1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2026年4月1日最近更新:
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
20
试验地点
1
主要终点
IOP

研究概览

简要总结

These procedures include deep non-penetrating sclerectomy, viscocanalostomy, and small incision trabeculectomy, avoiding Tenon's capsule.

详细描述

Since the advent of GATT or phacogoinotomy as MIGS, ab-externo canaloplasty and NPDS have become essentially obsolete. The ab-interno techniques to vasodilate Schlemm's canal and goniotomy have largely replaced ab-externo canaloplasty.

. Although the GATT procedure and phacogoinotomy is, minimally invasive methods, yet it needs normal functional collector orifice and not respect physiological function of trabecular meshwork,8 as these procedures depend mainly on incision and damage of trabecular meshwork360 degree in GATT 120 in goniotomy, the main disadvantage of these procedures it is not so suitable for narrow angle glaucoma and have many complications as post operative hyphemia with IOP spike, PAS, corneal injury and create cyclodialysis Moreover trabecular meshwork and Schlemm's canal are vital structures can repair themselves through limbal stem cells or even peripheral iris can cover the incision as the part of repair. The main disadvantage is that the trabeculectomy should not be relied upon when the target IOP is in the low teens. Also, these procedures are expensive and need a long learning curve, hyphemia can prevent completion of the operation.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
21 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients had combined phaco surgery with GATT.
  • All patients had phaco with goinopuncture.

排除标准

  • Healthy patient.
  • No history of phaco surgery with GATT or goinopuncture.

研究组 & 干预措施

Modified Trabeculectomy

Experimental

failure of combined phaco with GATT

干预措施: Modified trabeculectomy (Procedure)

结局指标

主要结局

IOP

时间窗: 24 hours

Intraocular pressure measurement

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hassan Lotfy Fahmy

Prof

Assiut University

研究点 (1)

Loading locations...

相似试验