Oral Manifestations Of Pediatric Cancer Patients Receiving Chemotherapy And Dental Awareness Among Parents
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 441
- 主要终点
- The assessment of the prevalence of oral adverse events induced by chemotherapy in pediatric cancer patients .
研究概览
简要总结
The prevention of oral illnesses in children and adolescents undergoing oncological treatment is critical, because oral lesions caused by this therapy significantly exacerbate the clinical condition and increase the risk of infection, as well as making it harder to perform required dental procedures when needed .
"The key to success in maintaining a healthy oral cavity during therapy is patient compliance. The child and the parents should be educated regarding the possible acute side effects." Pediatric cancer patients may have a lower quality of life if they have poor dental health. Preventing and treating pre-existing oral illnesses is critical to reduce problems in these people.
It is critical to raise awareness of the benefits of proper oral health so that this understanding becomes a positive attitude, reducing the discomfort of these children.
The American Academy of Pediatric Dentistry (AAPD) recommends pediatric oncology/hematology that Pediatric dentists must be involved in the treatment process from the moment cancer is diagnosed. This should be carried out by having a preventive and dental care plan developed based on the patient's needs before any cancer treatment is initiated.
The aim of the study is primarily to report oral complications and manifestations during chemotherapy treatment in pediatric cancer patients and raise the awareness of their parents on these manifestations thus proper interventions can be carried out to prevent more serious problems.
详细描述
Childhood cancer is defined here as cancer in children aged 0-14 years and it only accounts for a small portion of the worldwide cancer burden .with an estimated 13.7 million additional cases of cancer in children globally between 2020 and 2050.
Childhood malignancies continue to be a leading source of morbidity and death in children. Cancer is the leading cause of disease-related mortality among children in developed, high-income countries, such as the United States.
With advances in healthcare access and a drop in communicable disease mortality, paediatric cancer is projected to become a significant cause of death even in developing, low- and middle-income nations. Furthermore, because children make up a significant proportion of the population in these countries, the scope of the problem is exacerbated, potentially resulting in a greater burden of childhood malignancy for the healthcare system to address.
Leukaemia accounted for the greatest share of classified childhood cancer burden globally, followed by brain and nervous system cancers.
The Children's Cancer Hospital in Egypt (CCHE) is the country's largest paediatric cancer hospital, enrolling about 3000 children under the age of 18 annually, accounting for an estimated 50% of juvenile cancer cases in a country with a population of around 100,000,000.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 1 Year 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children between the age of 1 -14years.
- •Children receiving chemotherapy for hematological cancer or solid tumors.
- •Parents who are able to understand the aim of the study and willing to participate in the study.
排除标准
- •Children previously received radiotherapy on head and neck region.
- •Children suffering from oral cancer.
- •Children presented with other oral disorders such as leukoplakia.
结局指标
主要结局
The assessment of the prevalence of oral adverse events induced by chemotherapy in pediatric cancer patients .
时间窗: Baseline
Patients will be examined for oral manifestations at the first visit together with intra oral photos will be taken for the patients included in the study. Voice ,swallow ,tongue, saliva, mucous membrane\*\*, gingiva ,teeth will be measured by Oral Assessment Guide by the principal investigator . \*\*If oral mucositis is present it will be staged according to the World Health Organization Scale (WHO Oral Toxicity Scale) by the principal investigator.
次要结局
- Assessment of dental awareness among parents of pediatric cancer patients .(Baseline)
研究者
Amira Mohammed Al-Sayed
Principal Investigator
Cairo University