Phase II Study of Immunotherapy With Autogenous Papilloma Vaccine in Patients With Recurrent Juvenile Papilloma of the Larynx

University of Medicine and Dentistry of New Jersey2 个研究点分布在 1 个国家开始时间: 2004年2月27日最近更新: 2011年7月26日

适应症

试验速览

阶段: 2 期
发起方: University of Medicine and Dentistry of New Jersey
试验地点: 2

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

RATIONALE: Vaccines made from papilloma virus cells may make the body build an immune response to and kill papilloma cells.

PURPOSE: Phase II trial to study the effectiveness of papilloma virus vaccine in treating young patients with recurrent papilloma of the larynx.

详细描述

OBJECTIVES: I. Determine the immune response in patients with juvenile papilloma of the larynx treated with autogenous vaccine derived from each patient's own tumor.

OUTLINE: Patients receive autogenous papilloma vaccine intradermally and subcutaneously weekly for 20 weeks.

PROJECTED ACCRUAL: Not specified

研究设计

研究类型: Interventional
主要目的: Treatment

入排标准

年龄范围: 1 Year 至 —（Child, Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•DISEASE CHARACTERISTICS: Diagnosis of severe recurrent juvenile papilloma of the larynx requiring surgery at least 4 times per year Condition must have existed for more than 1 year
•PATIENT CHARACTERISTICS: Age: 1 and over Performance status: Not specified Life expectancy: Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified
•PRIOR CONCURRENT THERAPY: See Disease Characteristics

排除标准

未提供

研究者

发起方

University of Medicine and Dentistry of New Jersey

申办方类型

Other

研究点 (2)

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