THE EFFECT OF PREOPERATIVE MIRABEGRON ON URETERAL ACCESS SHEATH INSERTION SUCCESS AND URETERAL INJURY DURING RETROGRADE INTRARENAL SURGERY: A RETROSPECTIVE COMPARATIVE STUDY
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 131
- 试验地点
- 1
研究概览
简要总结
The aim of this study is to evaluate whether there is a difference in the passage rate of the ureteral access sheath between patients who used mirabegron (a beta-3 receptor agonist) for overactive bladder and those who underwent retrograde intrarenal surgery for kidney stones, and those who did not use mirabegron. Considering that beta-3 receptors in the smooth muscle of the ureter cause relaxation in the ureter, the hypothesis that the passage rate of the access sheath increases in those using mirabegron, thus facilitating access to kidney stones and improving surgical success, will be investigated.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients scheduled for RIRS due to kidney stones
排除标准
- •preoperative ureteral stenting,
- •ureteral strictures, history of ureteral or bladder surgery,
- •anatomical abnormalities of the urinary tract,
- •active urinary tract infection,
- •pregnancy,
- •uncontrolled hypertension (systolic blood pressure ≥180 mmHg, diastolic blood pressure ≥110 mmHg),
- •use of medications affecting ureteral smooth muscle tone
研究组 & 干预措施
Mirabegron Group
Patients using mirabegron for overactive bladder and scheduled for retrograde intrarenal surgery due to kidney stones.
干预措施: Retrograde intrarenal surgery (Procedure)
Control Group
Not using mirabegron and scheduled retrograde intrarenal surgery due to kidney stones.
干预措施: Retrograde intrarenal surgery (Procedure)
研究者
Arif Bedirhan Bayraktar
UROLOGIST
Ankara Training and Research Hospital