NCT01206361已完成不适用
Persistence Of Use Of Topical Prostaglandin Fixed Dose Combination In The United Kingdom Primary Care: An Observational Study In Thin
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.0 个研究点目标入组 2,015 人开始时间: 2010年2月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2,015
- 主要终点
- Frequency distribution of persistent and non-persistent patients across study cohorts
研究概览
简要总结
The hypothesis is that there is no difference in persistency between Xalacom and the alternative fixed dose combination products (Duotrav and Ganfort) over a 12 month period.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who had received a prescription for either Xalacom, Ganfort and DuoTrav
- •Greater than 18 years old
- •Diagnosed with glaucoma or ocular hypertension
- •Registered at the primary care practice for > 12 months
排除标准
- 未提供
研究组 & 干预措施
fixed dose prostaglandin combination
干预措施: XALACOM (Drug)
fixed dose prostaglandin combination
干预措施: Duotrav (Drug)
fixed dose prostaglandin combination
干预措施: Ganfort (Drug)
结局指标
主要结局
Frequency distribution of persistent and non-persistent patients across study cohorts
时间窗: 12 months
Frequency distribution of switchers, re-starters and discontinuing patients as well as patients commencing add-on therapy across the study cohorts
时间窗: 12 months
Time to discontinuation of each cohort
时间窗: 12 months
次要结局
- Age and sex: Townsend Score of social deprivation, time since first THIN diagnosis of glaucoma or ocular hypertension(12 months)
- Procedures: Laser, Trabeculectomy, viscocanalostomy, deep sclerectomy(12 months)
- Ocular Pharmacological Treatments: Beta-blockers and Alpha-agonists(12 months)
- Prostaglandin mono-therapies(12 months)
- The cohort of patients which were evaluated in this study were investigated for the presence of history of disease for asthma, cardiovascular disease, diabetes, renal failure and systemic hypertension. The number of patients in each cohort were(12 months)
- presented who had had (i) a 12 month history of any of the diseases or (ii) had had a history of any of the diseases.(12 months)
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