临床试验/NCT07736248

NCT07736248尚未招募不适用

Super Selective Angiographic Catheterization and Embolization of Genicular Arteries for Treatment of Symptomatic Knee Osteoarthritis

Assiut University0 个研究点目标入组 30 人开始时间: 2026年8月1日最近更新: 2026年8月4日

适应症

试验速览

阶段: 不适用
状态: 尚未招募
发起方: Assiut University
入组人数: 30
主要终点: change from baseline in visual analog scale (VAS) pain score

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

To evaluate the efficacy and safety of genicular artery embolization in patients with symptomatic knee osteoarthritis refractory to conservative treatment.

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 18 Years 至 70 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Clinical diagnosis of knee osteoarthritis according to the criteria of the American College of Rheumatology.
•Radiographic evidence of osteoarthritis corresponding to Kellgren-Lawrence grades I-III.
•Moderate to severe knee pain for at least 6 months. Visual Analog Scale (VAS) score ≥
•Failure of conservative treatment for at least 3 months including analgesics, non-steroidal anti-inflammatory drugs, physiotherapy, lifestyle modification, or intra-articular injections.

排除标准

•Kellgren-Lawrence grade IV osteoarthritis.
•Previous knee arthroplasty.
•Inflammatory arthropathies such as rheumatoid arthritis, psoriatic arthritis, or gout.
•Active local or systemic infection.
•Severe peripheral arterial disease.
•Coagulation disorders.
•Renal insufficiency (raised renal chemistry).
•Known allergy to iodinated contrast media.
•Refuse to provide written informed consent

结局指标

主要结局

change from baseline in visual analog scale (VAS) pain score

时间窗: Baseline and 6 months after the Procedure

pain intensity measured using the 10-cm visual analog scale (VAS). scores range from 0 to 10, with higher scores indicating greater pain. The change from baseline to 6 months after genicular artery embolization will be assessed.

次要结局

Technical Success Rate of Genicular Artery Embolization(During the procedure)
Change from Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Total Score(Baseline, 3 months, and 6 months after the procedure)
Change from Baseline in Health-Related Quality of Life Score (EQ-5D-5L)(Baseline and 6 months after the procedure)

研究者

发起方

Assiut University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Rehab Awad Mohamed Ahmed

principal investigator

Assiut University

相似试验

招募中

不适用

Percutaneous Transcatheter Genicular Embolization in Osteoarthritis

NCT07361198Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.20

招募中

不适用

Transcatheter Arterial Embolization Using Nexsphere-F for Chronic Shoulder Pain Refractory to Conservative Treatment

NCT07336849Chung-Ang University Hosptial, Chung-Ang University College of Medicine44

尚未招募

不适用

Comparison of two pain mitigation strategies of a minimally invasive surgical technique in patients suffering from plantar fasciitis, which is refractory to medical management

CTRI/2025/11/097656Self24

招募中

4 期

The purpose of this clinical investigation is to assess the safety and performance of the diagnostic catheter when used in angiographic procedures. This study aims to generate clinical evidence supporting the safe and effective use of the device in real-world settings.

CTRI/2025/08/093386POLY MEDICURE LIMITED73

尚未招募

不适用

Genicular artery embolisation and the effect on Knee Osteoarthritis - a randomised controlled trial.Musculoskeletal - OsteoarthritisKnee osteoarthritis

ACTRN12622001157763South Western Sydney Local health District54