Assessment of the Impact of Gadolinium Injection on the Measurement of the QSM Signal
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 73
- 试验地点
- 1
- 主要终点
- mean of the delta observed between the QSM of the white matter before and after injection of gadolinium
研究概览
简要总结
Patients meeting the inclusion and non-inclusion criteria will be offered to participate in the study. If they agree, they will perform an MRI without injection to obtain the QSM then perform the MRI with injection that was prescribed to them as part of the care, then they will perform a second time the MRI without injection to obtain the QSM. They will also answer a short questionnaire documenting their previous exposure to gadolinium.
详细描述
Patients meeting the inclusion and non-inclusion criteria will be offered to participate in the study. If they agree, they will perform an MRI without injection to obtain the QSM then perform the MRI with injection that was prescribed to them as part of the care, then they will perform a second time the MRI without injection to obtain the QSM. They will also answer a short questionnaire documenting their previous exposure to gadolinium.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients over 18 years old
- •with an inflammatory CNS pathology
- •to benefit as part of care from an MRI with injection of gadolinium
- •consent to participate in the study
- •beneficiary of a social protection scheme
排除标准
- •pregnant or breastfeeding woman
- •patient benefiting from a legal protection measure
- •Patient having performed more than 3 MRI exams with gadolinium injection during his life
- •Secondary exclusion criteria :
- •motion artifact not allowing image interpretation
- •patient who has not completed one of the following sequences: T1 anatomical, FLAIR, or QSM pre-gadolinium injection.
- •Secondarily excluded patients will be replaced up to a maximum of 25 patients.
结局指标
主要结局
mean of the delta observed between the QSM of the white matter before and after injection of gadolinium
时间窗: 1 DAY
mean of the delta observed between the QSM of the white matter before and after injection of gadolinium
次要结局
未报告次要终点