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临床试验/NCT06737432
NCT06737432进行中(未招募)不适用

Respiratory Knowledge Portal Application to Reduce Ventilator Associated Events, Ventilator Induced Lung Injury and Alarm Parameter Variance

The University of Texas Medical Branch, Galveston3 个研究点 分布在 1 个国家目标入组 875 人开始时间: 2024年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
875
试验地点
3
主要终点
Number of participants with Ventilator-Associated Events

研究概览

简要总结

Ventilator associated events (VAE) is a quality metric defined by 48 hours of stability followed by 48 hours of escalation of ventilator settings within the ICU. VAE have been associated with poor outcomes and increases the cost of care, yet is not easy to avoid. Operationalizing all the standards of care known to improve outcomes of those requiring mechanical ventilation in the critical care environment requires a comprehensive approach. ICU teams are encouraged to follow best practice protocols to help liberate and prevent VAEs. Yet, compliance with protocols in most ICUs is suboptimal for multiple reasons. With the advent of computerized mechanical ventilators capable of streaming data from breath to breath and biomedical integration systems (BMDI) such as Capsule (UTMB's BMDI system), software systems have been developed to help identify variances in the standard of care. Automation in near real-time ventilator data feedback has been shown to reduce the incidences of VAEs.

This quality improvement project will leverage Vyaire's Respiratory Knowledge Portal (RKP) to collect and store meaningful data regarding ventilator-associated events (VAE), alarm policy compliance, ventilator weaning, and lung protective analytics.

Goals:

  1. To collect quality metrics utilizing RKP from patients requiring mechanical ventilation over a 3-4-month period for a retrospective baseline analysis.
  2. Provide the RKP tool to the ICU team to determine if the use of RKP's webportal and Messenger Zebra phone app improves quality of mechanical ventilation and outcomes.
  3. To determine a return on investment (ROI) for a software system like RKP.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Sequential
主要目的
Health Services Research
盲法
None

盲法说明

Monitoring 3-4 months prior to intervention or use of the software.

入排标准

年龄范围
— 至 100 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Subjects requiring invasive mechanical ventilation.
  • Subjects is in one of the monitored Galveston campus ICUs.

排除标准

  • Is in an ICU not monitored by RKP.
  • Adults on high frequency ventilation (pediatric patients are NOT excluded).
  • Any patient requiring ECMO.

研究组 & 干预措施

Control

No Intervention

We will monitor without clinician use of the software.

Use of RKP

Active Comparator

Use of RKP alerts to the standard of care.

干预措施: RKP Monitoring Software (Other)

结局指标

主要结局

Number of participants with Ventilator-Associated Events

时间窗: 3-4 months

次要结局

  • Number of Ventilator Alarm Set Outside of Compliance(3-4 months)
  • Duration of Days on mechanical ventilation(3-4 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (3)

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