NCT04520672招募中不适用
Circulating Tumor Cells (CTC) in Cancer
University Hospital, Basel, Switzerland2 个研究点 分布在 1 个国家目标入组 3,000 人开始时间: 2020年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 3,000
- 试验地点
- 2
- 主要终点
- Overall survival (OS) in heterogeneous cancer population
研究概览
简要总结
This observational study with circulating tumor cells (CTC) count, isolation and analysis at several time points during disease progression is to investigate the role and biology of CTCs and clusters of CTCs in different cancer types. It also evaluates the role of CTCs as biomarkers, and aims at the identification of key signaling networks that are active in CTCs.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult cancer patients
- •All patients with histology-based proved diagnosis of cancer, all stages and subtypes can be included. Precancerous lesions cannot be included.
- •All patients with the diagnosis of a solid tumor including adenocarcinoma, squamous cell carcinoma, neuroendocrine carcinoma, sarcoma
- •Written pathology report must be available.
- •Written informed consent.
排除标准
- •No written informed consent.
- •No proved diagnosis of malignancy by pathology report.
- •Patients with the diagnosis of blood cancer
结局指标
主要结局
Overall survival (OS) in heterogeneous cancer population
时间窗: Screening (Visit 1) until the date of death (assessed up to 240 months)
overall survival (OS) in heterogeneous cancer population
Change in total number of isolated CTCs
时间窗: Through study completion, an average of 20 years
Change in total number of isolated CTCs
次要结局
- Progression free survival (PFS)(Through study completion, an average of 20 years)
研究者
研究点 (2)
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