NCT04309994已完成不适用
Combined Use of a Novel Cardioplegic Formula With MPS® Versus Cardioplexol ® in Urgent Isolated CABG Using MiECC in Patients With Recent Acute Myocardial Infarction
University Hospital, Basel, Switzerland1 个研究点 分布在 1 个国家目标入组 307 人开始时间: 2010年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 307
- 试验地点
- 1
- 主要终点
- myocardial damage
研究概览
简要总结
The goal of this study is to compare the two cardioplegia solutions (blood cardioplegia by means of MPS ® vs. Cardioplexol ®) regarding perioperative outcome and with special attention to cardiac markers in patients with a recent heart attack.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent a CABG using MPS® or Cardioplexol ®
- •Heart attack less than 7 days before surgery
排除标准
- •use of other cardioplegia solution than Cardioplexol ® or MPS®
- •other inventions than CABG
- •explicit will of the patient that his data may not be used
- •denied general consent
结局指标
主要结局
myocardial damage
时间窗: patients with that received a coronary artery bypass grafting and that were treated (for approximately 15 days) at the University Hospital between February 2010 and January 2020 (data taken perioperative during hospital stay for CABG)
Analyse cardiac biomarkers as indicators for myocardial damage: high sensitive troponin (Ths-TrT, ng/mL), creatine kinase (CK, in ng/mL) and creatine kinase-MB isoenzyme (CK-MB, in ng/mL)
次要结局
- 30 days Mortality(30 days after CABG)
- length of stay in the intensive care unit(perioperative during hospital stay for CABG (for approximately 15 days))
- Number of participants with bleedings(perioperative during hospital stay for CABG (for approximately 15 days))
- Number of participants with postoperative arrhythmia(perioperative during hospital stay for CABG (for approximately 15 days))
研究者
研究点 (1)
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