Propolis In The Treatment Of Chronic Periodontitis - A Clinicomicrobiologic Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change in the probing pocket depth and clinical attachment level
研究概览
简要总结
This study was conducted to evaluate by clinical and microbiological parameters the effect of locally delivered propolis as an adjunct to scaling and root planing in the treatment of chronic periodontitis.
详细描述
Materials and Methods
20 subjects diagnosed with chronic periodontitis were recruited to participate in split-mouth design and provided informed consent. Subgingival plaque sampling and clinical recording at baseline, 15 days and 1 month was performed. The patients received scaling and root planing, followed by Propolis administration subgingivally in the test sites. Significant differences between test and control were evaluated using the Mann-Whitney U test and Wilcoxon rank test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 25 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •good general health
- •chronic periodontitis
- •minimum of 20 natural teeth with at least one pocket per quadrant
- •probing depth (PD) between 5 and 8 mm.
排除标准
- •subgingival instrumentation within 3 months
- •antibiotic therapy within 3 months prior to the start of the study;
- •pregnant or nursing women
- •intolerance or allergy to honey products
研究组 & 干预措施
Propolis
干预措施: scaling root planing (Procedure)
Propolis
干预措施: Propolis (Drug)
scaling and root planing
干预措施: scaling root planing (Procedure)
结局指标
主要结局
Change in the probing pocket depth and clinical attachment level
时间窗: three time points of baseline,2 weeks, 4 weeks
次要结局
- change in gingival index and microbiological changes(three time points baseline, 2 weeks, 4 weeks.)
研究者
NEHAL N SANGHANI, mds
DR.
Rajarajeswari Dental College & Hospital