NCT00033033已完成2 期
Phase 2, Double-Blind, Placebo-Controlled Trial of Reserpine for the Treatment of Cocaine Dependence
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 140
- 试验地点
- 3
- 主要终点
- Cocaine use
研究概览
简要总结
The purpose of this study is to assess the efficacy and safety of reserpine for the treatment of cocaine dependence.
详细描述
To assess the efficacy and safety of reserpine in reducing cocaine use in subjects with cocaine dependence. This is a double-blind, placebo-controlled, parallel-group design with a 2 week baseline period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Be at least 18 yrs of age; DSM-4 diagnosis of cocaine dependence; treatment seeking individuals; have the ability to understand and provide written informed consent; females of child bearing potential using appropriate birth control method
排除标准
- •Additional criteria available during screening at the site.
结局指标
主要结局
Cocaine use
Addiction severity
Cocaine withdrawal
Adverse events
Clinical improvement
次要结局
未报告次要终点
研究者
研究点 (3)
Loading locations...
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