Bioavailability of phosphorus after oral intake of two hypoallergenic infant formulas in healthy adult volunteers with a neutral stomach pH - UP2

utricia Research0 个研究点目标入组 36 人开始时间: 待定最近更新: 2024年4月15日

试验速览

暂无简介。

•- Age * 18 and * 40 years
•- Body Mass Index (BMI) * 18.5 and * 24.9 kg/m2
•- Non-Asian race*
•- Willingness and ability to comply with the protocol
•- Willingness to use a method of birth control during participation in the study (only women)
•- Written informed consent
•- Judged by the investigator to be in good health;*(A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including, for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam)

•- Any medical condition that interferes significantly with digestion and/or gastrointestinal (GI) function (e.g. inflammatory bowel disease, gastroesophageal reflux disease, celiac disease. diaphragmatic hernia or diaphragmatic surgery, gastric ulcer, gastritis, (gastro)enteritis, gall bladder problems, pancreatitis, GI cancer, oesophageal and/or gastric surgery), in opinion of the investigator.
•- Known renal or hepatic failure or known thyroid dysfunction
•- Known food allergy and/or food intolerance for: cow*s milk, lactose, peanuts, nuts, wheat, soy, potato, carrot, onion, tomato, corn, apple and/or orange
•- Any ongoing cancer (except for basal cell carcinoma) and/ or cancer treatment
•- Serum 25(OH)D of < 50 nmol/l at screening
•- Haemoglobin (Hb) in men <7.5 mmol/l and in women <7.0 mmol/l at screening
•- Use of any medication within 1 week of Visit 1 except for oral contraceptive, incidental use of paracetamol and/or nonsteroidal anti-inflammatory drugs (e.g. ibuprofen and aspirin) and/or common cold relievers (e.g. nasal sprays containing xylometazoline and sore throat relievers), if medically justified in opinion of the investigator.
•- Known hypersensitivity to esomeprazole, and fructose-intolerance, glucose-galactose malabsorption, sucrase-isomaltase insufficiency
•- Use of nutritional supplements (other than vitamin D) within two weeks of Visit 1
•- Unsuccessful placement of a cannula for taking blood samples at Visit 1

发起方

utricia Research