Treatment of Acute Lower Limb Ischaemia in Sweden 1994-2014
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16,287
- 主要终点
- Amputation-free survival
研究概览
简要总结
Study of acute lower ischemia therapies based on data collected from the Swedish Vascular Surgery Registry between 1994 and 2014.
Primary endpoint is long term amputation-free survival and secondary end-points are 30 days and 1 year amputation-free survival as well as different revascularization techniques results and time trends.
详细描述
The prospective Swedish Vascular Registry (Swedvasc) started in 1987 and since 1994 it has included more than 95 percent of the vascular surgical procedures performed nationwide. The registry has received extensive high internal and external validation. Roughly 16000 open surgical and endovascular revascularisation procedures for acute limb ischemia have been performed during this period of time.
The fact that every Swedish citizen has a unique personal identification number makes it possible to obtain 100 percent accurate survival and amputation data. Survival data were obtained through crosschecking the personal identification number with the national population registry in June 2016.
This offers a unique opportunity to study a large population-based cohort of unselected patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with acute limb ischemia
- •Surgical procedure performed between 1 January 1994 and 31 December 2014 in Sweden and registered in the Swedvasc registry
- •Infrainguinal occlusions
排除标准
- •Acute limb ischemia secondary to trauma, bleedings, dissection or graft infections.
- •Suprainguinal occlusions.
结局指标
主要结局
Amputation-free survival
时间窗: 1-22 years
Combined endpoint with death and amputation. Either the leg is amputated and/or the patient is dead or the patient is alive without major amputation.
次要结局
- Survival(1-22 years)
- Complications 30 days after surgery(30 days)
- Amputation(1-22 years)
研究者
Martin Bjorck
Professor of Vascular Surgery
Uppsala University Hospital