Oral intake of new full spectrum hyaluronan improves skin profilometry and aging factors: a randomized, double-blind, placebo-controlled clinical trial

Complife Italia Srl0 个研究点目标入组 60 人开始时间: 2020年11月2日最近更新: 2022年3月28日

适应症

试验速览

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34933842/ (added 15/03/2022)

•1. Healthy female subjects, showing mild to moderate signs of skin aging
•2. Aged between 35 and 70 years old
•3. Caucasian ethnicity
•4. Observed an adequate wash-out period from similar studies
•5. Give informed consent
•6. Agree not to make any changes to their normal everyday routine
•7. Agree not to use products with comparable activity to the study product
•8. Agree not to expose in an intensive way to UV rays during the whole study duration
•9. Available to take food supplements and comply with the study protocol
•10. Agree to adopt an adequate contraceptive system

•1. Eating disorders (such as bulimia and anorexia)
•2. Pregnant, breastfeeding or have planned a pregnancy during the study period
•3. Previous history of gastrointestinal pathological conditions
•5. Systemic pharmacological treatment
•6. Under local pharmacological treatment on the skin area monitored during the test
•7. Congenital or acquired immunodeficiency
•8. Under treatment with food supplements which could interfere with the functionality of the product being study
•9. Other skin alterations on the monitored area
•10. Exposed in intensive way to UV rays during the 4 weeks prior to the study start
•11. Considered as not suitable to participate in the study by the investigator
•12. Reported food intolerance to one or more ingredients contained in the food supplement
•13. Alcohol addiction
•14. Drug addiction

发起方