Shanghai Clinical Cohort - Adrenal Disease
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- Treatment Response Rate
研究概览
简要总结
As a vital organ responsible for producing life-sustaining hormones, the adrenal gland is associated with a wide range of diseases. These diseases affect multiple systems throughout the body and carry a high rate of mortality and disability. Current diagnosis and treatment face several challenges: significant variability in hormone testing results, inaccurate localization via imaging techniques, unclear molecular characteristics of adrenal tumors, and difficulty in determining prognosis through pathology. Therefore, establishing a clinical research cohort for adrenal diseases is essential. Such a cohort will enable in-depth exploration of disease mechanisms, identification of disease subtypes, optimization of diagnostic criteria, evaluation of treatment efficacy, advancement of personalized medicine, and formulation of prevention and treatment strategies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A signed and dated informed consent form
- •Commitment to abide by the study procedures and cooperate with the implementation of the entire study process
- •Patients diagnosed with adrenal diseases, including aldosteronism, Cushing's syndrome, pheochromocytoma, adrenocortical carcinoma, and congenital adrenal hyperplasia; regardless of whether they have received adrenal surgery, radiotherapy, and/or medication therapy
- •Aged between 18 and 75 years
排除标准
- •Subjects meeting any of the following criteria will be excluded from this study:
- •Refuse to sign the informed consent form
- •Patients without adrenal diseases
- •Have specified diseases or conditions (physical or psychological, identified through physical examination) that warrant exclusion from the study
结局指标
主要结局
Treatment Response Rate
时间窗: at least six months or more
Post-Treatment Remission Rate
时间窗: at least six months or more
次要结局
未报告次要终点
研究者
Wang Weiqing
Director of the Department of Endocrinology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Ruijin Hospital