Tissu Adipeux épicardique et rigidité artérielle Chez Les Personnes Vivant Avec un diabète
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Epicardial fat volume
研究概览
简要总结
The present study is a retrospective and prospective current care cohort that will allow us to evaluate the relationship between epicardial fat volume and increased arterial stiffness in a person living with diabetes.
详细描述
Epicardial adipose tissue is considered as the cardiac visceral fat and is associated with increased cardiovascular risk, for example in diabetes. Thus, the mechanisms involved seem to be related to myocardial lipotoxicity; atherosclerosis in connection with inflammation and secretion of proinflammatory factors such as cytokines but also insulin resistance.
In this context, the investigators hypothesize that epicardiac adipose tissue volume will be higher in patients with increased arterial stiffness than in those without. In this study, the investigators will then try to verify the existence of a relationship between pericardial adipose tissue volume and increased arterial stiffness in people living with diabetes.
To do this, the investigators will analyze the results of measurements of pericardial fat volume, coronary calcium score, and pulse wave velocity in diabetic patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients will be eligible for participation in the study if:
- •They are informed and have not objected to participating in the research.
- •They have type 1 or 2 diabetes.
- •They perform a coronary calcium score measurement by CT scan and a pulse wave velocity assessment during their routine care practice.
排除标准
- 未提供
结局指标
主要结局
Epicardial fat volume
时间窗: the inclusion visit
Epicardial fat volume will be determined using cardiac CT scan without contrast injection.
次要结局
未报告次要终点