The Effect of Anterior Corneal Incisions on Intraoperative Floppy Iris Syndrome (IFIS) Incidence and Severity in Tamsulosin Treated Cataract Patients
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- the number of IFIS cases observed during operation.
研究概览
简要总结
Intraoperative Floppy Iris Syndrome (IFIS) may occur during cataract surgeries in patients treated with alpha 1 blockers. IFIS related to alpha 1 blocker Tamsulosin (used for prostate hypertrophy) was reported in 50-90% of patients. IFIS during surgery make the surgery more difficult and raise complication rate.
Using anterior corneal incisions was reported briefly in literature as a prophylactic means but was not studied prospectively. we believe (according to our clinical experience) that these anterior incisions do help to reduce the incidence and severity of IFIS signs and complications rate during surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •cataract candidates treated (in the present or in the past) with tamsulosin
- •aged 55 or more
- •candidates for topical anesthesia
- •no allergy to anticholinergic or adrenergic drugs
- •able to understand and sign an informed consent
排除标准
- •history of uveitis
- •iris neovascularization
- •s/p iris surgery
- •traumatic/uveitis induced cataract
- •dialysis / abscence of zonules
研究组 & 干预措施
anterior corneal incision
干预措施: anterior (more central) corneal paracentesis incision (Procedure)
结局指标
主要结局
the number of IFIS cases observed during operation.
时间窗: during the operations
次要结局
- assessing the clinical grade of observed IFIS cases(during the operations)