Effect of Visuospatial Training Tasks on Freezing of Gait in Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Double Limb Support (DLS)
研究概览
简要总结
This study is designed to evaluate whether a specific visuospatial training task will change gait performance of Parkinson's disease (PD) patients in doorways, specifically freezing of gait.
详细描述
This study is a randomized, prospective, single-blinded six-week study in PD patients with freezing of gait (FOG).
This study will involve 2 study groups:
Group A - training group; Group B - no training group/controls.
Both groups will complete a gait evaluation and neuropsychological testing. Group A will also practice an in-home visuospatial task for 30 minutes, 4-6 days per week for six weeks. Group B will not complete the in-home tasks.
Participation in this study is expected to last 6-8 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: greater than 18 years old and without an upper age limit
- •diagnosis of idiopathic PD exhibiting at least 2 or 3 cardinal signs (bradykinesia, rigidity, and resting tremor)
- •Ambulate independently without an assistive device for at least 60 meters
- •Freezing of gait episodes confirmed through the FOG-Q and evaluation by a fellowship trained Movement Disorder neurologist
- •Willingness and ability to participate in training and complete training diary
- •Documented FOG-Q and Unified Parkinson's Disease Rating Scale (UPDRS) II
- •Ability to sign informed consent
- •Pregnant females will be included in the study and there are no known risks to the pregnant female or fetus
排除标准
- •Inability to complete questionnaires
- •Unwillingness to participate in training, complete all questionnaires and training diary
- •Subjects with secondary causes of parkinsonism
- •Significant dementia (MOCA <20)
- •Prior deep brain stimulation (DBS) surgery or pallidotomy
- •Subjects cannot participate in any form of Physical Therapy, Occupational Therapy or Speech Therapy during the study period
- •Subjects cannot start any new medications during the study period.
结局指标
主要结局
Double Limb Support (DLS)
时间窗: 6 weeks
Primary outcome will be the percent of the gait cycle spent in DLS. This will be evaluated using a GaitRite via a continuous walk, with subjects walking an 18-20 meter oval loop three times continuously.
次要结局
未报告次要终点