Housing, Environment, And Living Conditions for Transformed Health (HEALTHe Birmingham)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 460
- 试验地点
- 2
- 主要终点
- Change in Patient-Reported Outcomes Measurement Information System (PROMIS-10) Global Health
研究概览
简要总结
This project will compare the health effects of public housing renovation, neighborhood built and social environment improvements, and indoor air purification, alone and in combination, as well as the cost effectiveness of each approach.
STUDY 1: The study will assess the effects of public housing and neighborhood environment (built and social) improvements on health-related behaviors, psychosocial and physiologic stress, and self-reported and physiological markers of lung health and chronic disease.
STUDY 2: The study will determine whether indoor air purification can positively impact lung health in public housing sites not undergoing housing renovation, comparing a site near industrial pollution vs one less contaminated.
详细描述
Participants will complete surveys, physical exam, lung function tests, and blood draw. An indoor air purifier with a usage tracker and an indoor air quality monitor will be provided, and used filters will be analyzed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 89 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults age 18 years and older
- •English speaking
- •Residents of one of 4 public housing site in Birmingham, Alabama
排除标准
- •Individuals who are not 18 years or older
- •Do not speak English
- •Do not meet the residency criteria
研究组 & 干预措施
Elyton Village Community
Participants will receive improved neighborhood environment (built and social) and indoor air purification.
干预措施: Indoor Air Purification (Other)
Elyton Village Community
Participants will receive improved neighborhood environment (built and social) and indoor air purification.
干预措施: Neighborhood Improvements (Other)
Southtown Court Community
Participants will receive new public housing.
干预措施: Housing Improvements (Other)
Smithfield Court Community
Participants will receive new public housing and improved neighborhood environment (built and social).
干预措施: Housing Improvements (Other)
Smithfield Court Community
Participants will receive new public housing and improved neighborhood environment (built and social).
干预措施: Neighborhood Improvements (Other)
Collegeville Community
Participants will receive indoor air purification.
干预措施: Indoor Air Purification (Other)
结局指标
主要结局
Change in Patient-Reported Outcomes Measurement Information System (PROMIS-10) Global Health
时间窗: Baseline, 12 months, 24 months
A self-reported measure of physical, mental, and social health. 10 item questionnaire T-score metric from zero to 100 where higher T-scores indicate better health.
Change in Allostatic load
时间窗: Baseline, 12 months
Measure of cumulative stress burden as the number of 10 indicators above a threshold: (1) serum albumin \<3.8 g/dL, (2) C Reactive Protein (CRP) \>3 mg/L, (3) High-Density Lipoprotein (HDL) \<40 mg/dL, (4) total cholesterol ≥240 mg/dL, (5) heart rate ≥90 beats/min, (6) systolic Blood Pressure (BP) ≥140 mmHg, (7) diastolic BP ≥90 mmHg, (8) serum creatinine ≥1.3 mg/dL, (9) Blood Urea Nitrogen (BUN) ≥18 mg/dL, and (10) waist circumference \>88 cm in women, \>102 cm in men.
Change in Indoor Air Quality
时间窗: Baseline, 6 months, 12 months (Study 2 only)
Particulate matter (PM2.5). Measures particles in the air that are 2.5 micrometers or smaller in diameter.
次要结局
- The percentage change in FEV1/FVC(Baseline, 6 months, 12 months (Study 2 only))
研究者
Gabriela R Oates
Associate Professor
University of Alabama at Birmingham