跳至主要内容
临床试验/NCT03974919
NCT03974919已完成不适用

Preoperative Pulmonary Systolic Pressure and Outcome After Non-Cardiac Surgery:Threshold Analysis

Peking University First Hospital1 个研究点 分布在 1 个国家目标入组 19,000 人开始时间: 2019年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
19,000
试验地点
1
主要终点
major adverse events

研究概览

简要总结

The linear or nonlinear relationship of pulmonary systolic pressure and cardiovascular and kidney outcome after non-cardiac surgery is unknown. This study is to explore the relationship of the two and try to identify the possible threshold of pulmonary systolic pressure for major cardio-vascular events after non-cardiac surgery.

详细描述

The linear or nonlinear relationship of pulmonary systolic pressure and cardiovascular and kidney outcome after non-cardiac surgery is unknown. This study is to explore the relationship of the two and try to identify the possible threshold of pulmonary systolic pressure for major cardio-vascular events after non-cardiac surgery.

Patients with preoperative cardio-echogram under going non-cardiac surgery were collected. The postoperative major cardiovascular, cerebral and kidney events were also identified and collected. Other data including peri-operative information and surgeries and anesthesia data were gathered.

Logistic regression models were built and selected. Independent risk factors relative to postoperative major cardiovascular and cerebral events were screened and identified. Odds ratio, relative risk and relative risk ratio of varies dichomitus cut points were calculated, trend breakpoint were identified, propensity score analysis were also done for causal inference.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • non-cardiac surgery patients with preoperative echocardiography records

排除标准

  • electronic records missing or peri-operative data missing

结局指标

主要结局

major adverse events

时间窗: 30 days postoperatively in hospital

cardiac infarction, heart failure, cardiac death, stroke, acute kidney injury

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yan Zhou, MD

Principal Investigator

Peking University First Hospital

研究点 (1)

Loading locations...

相似试验

Preoperative Pulmonary Systolic Pressure and Outcome... | 临床试验