ISRCTN14693054已完成未知
A randomised crossover design study comparing the pharmacokinetics and pharmacodynamics of two single Doses of ORal Aspirin (75 mg v150 mg) in pregnant women at risk of pre-eclampsia (DORA)
ewcastle upon Tyne Hospitals NHS Foundation Trust0 个研究点目标入组 16 人开始时间: 2021年3月9日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 16
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •1. Pregnant women at risk of pre-eclampsia according to NICE criteria
排除标准
- •1. Hypersensitivity to aspirin, salicylic acid compounds, or prostaglandin synthase inhibitors (e.g. certain asthma patients who may suffer an attack or faint)
- •2. Active, or history of, recurrent peptic ulcer and/or gastric/intestinal haemorrhage, or other kinds of bleeding such as cerebrovascular haemorrhage
- •3. Haemorrhagic diathesis or coagulation disorders such as hemophilia and thrombocytopenia
- •4. Severe hepatic or renal impairment
- •6. Taken aspirin over the preceding 4 weeks
- •7. Current anticoagulant therapy
- •8. Unable to give informed consent
- •9. Multiple pregnancy
- •10. Known fetal anomaly
- •11. Vegetarian/vegan diet
研究者
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