Vegetarianism And Grape PolyphenolExtract Supplementation On CognitionAnd Neuropsychological Status Of Healthy Adults
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- The subjects will get free nutritional screening & body composition analysis so as to help them make informed food choices to improve their cognition & help prevent the early occurrences of diseases like Dementia and Alzheimer’s. The post assessments will also be done to help improve cognition for those participants with mild dementia or memory loss. After receiving the grape polyphenol extract supplementation, older adults will have improved cognition , neuropsychological health and better quality of life.
研究概览
简要总结
Ageing is a common process that is connected with deteriorating health status and diet is one of the modifiable factors for preventing age-related diseases and preserving overall good health status during aging. Premature chronic diseases in older adults can be prevented by nutrition education and diet interventions. Polyphenols, which are derived from fruits and vegetables have antioxidants, antibacterial, anti-aging, anticancer, antidiabetic and anti-inflammatory properties. Furthermore, inflammation and oxidative stress play a huge role in cognitive decline, which eventually leads to age related diseases like dementia and Alzheimer’s, therefore, this intervention will utilize the polyphenol extract from fresh grape seeds which have natural compounds such as resveratrol known for their antioxidant and anti-inflammatory properties to improve the cognitive function as well as the neuropsychological status of adults in Hyderabad. This randomized trial will have both the pilot and main study, with the first phase of the study being an observational study to assess the effect of vegetarianism in cognition and neuropsychological status of healthy status.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 89.00 Year(s)（—）
- 性别
- All
入选标准
- •MMSE score ≥23 Willing to participate and giving informed consent.
- •Speaks and understand English and Telugu.
- •Subjects with no history of renal diseases.
排除标准
- •Subjects with severe cognitive impairment and prior cardiovascular and chronic diseases.
- •Subjects with acute psychiatric or neurological disease or those taking psychiatric and cognitive functioning medication.
结局指标
主要结局
The subjects will get free nutritional screening & body composition analysis so as to help them make informed food choices to improve their cognition & help prevent the early occurrences of diseases like Dementia and Alzheimer’s. The post assessments will also be done to help improve cognition for those participants with mild dementia or memory loss. After receiving the grape polyphenol extract supplementation, older adults will have improved cognition , neuropsychological health and better quality of life.
时间窗: 12 weeks after the intervention schedule
次要结局
未报告次要终点