The Effect of Semi-solid Feeding After Percutaneous Endoscopic Gastrostomy (PEG) on Clinical Outcomes, Specifically the Incidence of Aspiration Pneumonia and Postoperative Length of Stay
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 136
- 主要终点
- Incidence of aspiration pneumonia
研究概览
简要总结
Percutaneous endoscopic gastrostomy (PEG) is a minimally invasive procedure for long-term enteral tube feeding in patients with insufficient oral intake. Although peristomal site infection is often noted as the most common adverse event after PEG tube placements, it is seldom life-threatening and considered a minor adverse event. Feeding-related adverse events have been identified as the main cause of death after PEG, with up to 50% of postoperative early mortality (30 days) being attributed to aspiration pneumonia. This may be related to the persistence of gastroesophageal reflux (GER) of enteral feed after gastrostomy, even though PEG have been demonstrated to be superior to nasogastric tube feeding in terms of preventing GER. It has been more than a decade since semi-solid feeds were developed as an alternative to conventional liquid feeds to prevent feeding-related adverse events. Unfortunately, there is limited published literature on this topic despite the wide usage of this feeding method in Japan. Amidst the growing popularity of this method and the introduction of National Healthcare Insurance coverage for semi-solid feed prescriptions, we initiated a semi-solid feed protocol along with our existing post-PEG feeding protocols in 2014.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients receiving gastrostomy tube placement in our hospital for enteral nutrition.
排除标准
- •Patients receiving gastrostomy tube placement for decompression
- •Patients with no gut usage more than 2 weeks before procedure
结局指标
主要结局
Incidence of aspiration pneumonia
时间窗: through study completion, average 90 days postoperation
次要结局
- Postoperative length of stay(through study completion, average 90 days postoperation)
研究者
Wong Toh Yoon
Chief Gastroenterologist
Hiroshima Kyoritsu Hospital
