Finding the Right Words in Neurogenic Communication Disorders: Naming of Objects and Actions, Communicative Strategies in Conversation and Effects of Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- Naming ability in the Object & Action Naming Battery
研究概览
简要总结
Every year thousands of persons suffer from brain damage resulting in anomia, that is, word finding difficulties affecting their ability to talk to other people. Anomia may be a result of stroke or of progressive neurological diseases such as Parkinson's disease or multiple sclerosis (MS). Word retrieval is dependent on a complex system of different neural networks and to name objects and activities can be affected to different degrees. The present project explores different aspects of naming ability in altogether 90 persons that has anomia related to stroke or to Parkinson's disease or MS. Furthermore, the communicative strategies and resources used by conversation partners in everyday conversational interaction and in care situations, affected by anomia are studied. Finally, the project includes a study of the effectiveness of a word finding training program based on stimulation of semantic and phonological networks in the brain, involved in the production of words. There is a lack of research on effects on communication from anomia in Parkinson's disease and MS and there is no research on anomia that investigates both object and action naming using a material adapted to the Swedish language. In the project quantitative and qualitative methods are used to explore and describe how persons with different neurogenic communication disorders can use different resources and communicative strategies to express themselves.
详细描述
Project out line
The main project consists of:
- A descriptive study of the occurrence and type of naming difficulties in people with stroke, Parkinson's disease or Multiple sclerosis (MS) where quantitative data is compared at group level, (study 1).
- A descriptive study in which word search strategies are investigated with both quantitative and qualitative methods (study 2).
- A series of three intervention studies examining the effect of treatment of anomia (studies 3-5).
Study 1: The relation between type of injury and ability to name objects and actions and complex semantic-pragmatic word fluency
Participants The project includes a total of 90 people with anomia: 50 subjects with anomia after stroke, 20 individuals with Parkinson's disease and 20 individuals with MS are recruited are recruited through patient associations and health care facilities in Västra Götaland and included consecutively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
The results are assessed by independent assessors blinded to when the data is obtained and from which group.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjective experience of word finding difficulties
- •Diagnosed left hemisphere stroke or Parkinson's disease or MS
- •With correction, sufficient hearing and vision to be able to participate in the assessment
- •Participants with stroke at least six months post-onset and documented location of injury.
排除标准
- •Mother tongue other than Swedish
- •Moderately or severely impaired comprehension
- •Other neurological injury or disease
- •Moderate-severe apraxia of speech or dysarthria
- •Fatigue or impaired attention deficit which prevents participating in intensive training
研究组 & 干预措施
Comprehension training
Comprehension training
干预措施: Comprehension training (Behavioral)
SFA treatment
Semantic feature analysis
干预措施: Semantic feature analysis (Behavioral)
结局指标
主要结局
Naming ability in the Object & Action Naming Battery
时间窗: At baseline before start of intervention and after 21 days, at completion the intervention program
A measure of change in ability to name forty pictures consisting of simple black and white drawings. There is a 20-second time limit for response for each picture. Number of correct objects and activities will be calculated separately (range 0-20) as well as summarized (range 0-40)
次要结局
- Naming of 20 individually chosen training words(At baseline before start of intervention and after 21 days, at completion the intervention program)
- Sustained change in naming of 20 individually chosen training words(At a twelve week follow up after the completion of the intervention)
- The Communication Outcome After Stroke (COAST) scale(At baseline before start of intervention and after 21 days, at completion the intervention program)
- The Stroke Aphasia Quality of Life (SAQOL-39)(At baseline before start of intervention and after 21 days, at completion the intervention program)
- Sustained change in the Stroke Aphasia Quality of Life (SAQOL-39)(At a follow up twelve weeks after completion of intervention)
- Sustained change in naming ability in the Object & Action Naming Battery(At a twelve week follow up after the completion of the intervention)
- Sustained change in the Communication Outcome After Stroke (COAST) scale(At a twelve week follow up after the completion of the intervention)
- Retelling of events in video clips(At baseline before start of intervention and after 21 days, at completion the intervention program)
- Sustained change in retelling of events in video clips(At a 12 week follow up after the completion of the intervention)
- The Communicative Participation Item Bank (CPIB)(At baseline before start of intervention and after 21 days, at completion the intervention program)
- Sustained change in the Communicative Participation Item Bank (CPIB)(At a 12 week follow up after the completion of the intervention)