ISRCTN97143849已完成未知
Effectiveness of antibiotic prophylaxis during surgical evacuation of the uterus for miscarriage management in low income countries: a multinational, randomised, double-blind placebo-controlled trial
niversity of Birmingham (UK)0 个研究点目标入组 3,412 人开始时间: 2013年4月17日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 3,412
研究概览
简要总结
- 2018 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/29685179 2. 2019 results in https://www.ncbi.nlm.nih.gov/pubmed/30865795 (added 14/03/2019) 3. 2018 systematic review in https://www.ncbi.nlm.nih.gov/pubmed/29739349 4. 2019 cost-effectiveness analysis in: https://www.ncbi.nlm.nih.gov/pubmed/31402008 (added 14/08/2019)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •1. Women with a spontaneous miscarriage (under 22 weeks gestation)
- •2. Women undergoing surgical evacuation of the uterus (by manual vacuum aspiration, suction curettage or sharp curettage)
- •3. Willing and able to give informed consent
排除标准
- •1. Induced abortion of pregnancy
- •2. Septic miscarriage or evidence of infection
- •3. Allergy to either of the antibiotics
- •4. Current antibiotic use, or antibiotic use in the 7 days preceding surgical evacuation
- •5. Current febrile illness (temperature < 38oC)
- •7. Other contraindication to doxycycline or metronidazole use
- •8. Patient with condition requiring immediate care e.g. severe haemorrhage
- •9. Age less than 16 years
研究者
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