Therapeutic effect of percutaneous electroacupuncture combined with adaptive biofeedback in the treatment of outlet obstructive constipation

Anhui Provincial Hospital0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1. There was evidence of outlet obstruction and met Rome IV diagnostic criteria for functional constipation
•2. Aged 18 to 65 years old male and female;
•3. Colonoscopy was performed in a Grade-A hospital one year before the enrollment to exclude intestinal cancer, ulcer, inflammation or other organic intestinal diseases;
•4. B-ultrasound examination was performed in a Grade-A hospital one year before admission to exclude hepatobiliary and pancreatic diseases;
•5. The patients with normal ECG examination in our center one month before admission (QT interval was within normal range).

•1. Have a history of abdominal surgery;
•2. Organic diseases of digestive system (including polyps, inflammatory bowel disease, tumor, celiac disease, lactose intolerance, etc.);
•3. Any antispasmodic and analgesic drugs, gastrointestinal motility drugs, acid inhibitors, microecological agents, antibiotics, antidepressants, etc. were used within 2 weeks before enrollment;
•4. B ultrasound examination of liver, gallbladder and pancreas diseases;
•5. People with hypertension and unstable blood pressure control;
•6. Patients with diabetes mellitus, thyroid disease, systemic sclerosis, systemic lupus erythematosus, etc;
•7. Patients with severe psychological disorders;
•8. pregnant women, lactating women or planned pregnancies;
•9. There are allergic patients taking polyethylene glycol 4000 powder;
•10. Observation contents:
•(1) Basic information collection;
•(2) Constipation symptom severity score pac-sym;
•(3) Constipation quality of life score pac-qol;
•(4) Anal sphincter pressure during defecation;
•(5) Changes of serum psychosomatic neurotransmitters (conditional units).

发起方

Anhui Provincial Hospital