NCT01084824已完成不适用
A Randomized Clinical Trial Examining the Efficacy of Treatment of Cutaneous Verruca Vulgaris in Adult Patients With Combined Liquid Nitrogen Cryotherapy and Topically Applied Cantharidin
North Idaho Dermatology1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2007年6月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Percentage of common warts cleared
研究概览
简要总结
The purpose of the study was to see if liquid nitrogen, a commonly used treatment for warts, is more effective if it is used alone, or if it is more effective if combined with cantharidin, a topical treatment also commonly used for warts (verruca vulgaris).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •common warts on non-genital, non-facial skin
- •otherwise healthy
- •between 18-65 and able to give informed consent
- •capable of tolerating treatment
排除标准
- •Poor tolerance or sensitivity to treatments in study
- •<18 years old; >65 years old
- •verruca plana or condyloma acuminata
- •immunosuppression or immune dysfunction
- •significant peripheral vascular disease
- •significant sensitivity to cold
- •epidermodysplasia verruciformis
- •mosaiform warts or periungual warts
研究组 & 干预措施
Liquid nitrogen and canthardin
Active Comparator
Liquid nitrogen applied to wart(s), then cantharidin 1% topical applied afterwards.
干预措施: Liquid nitrogen and cantharidin (Drug)
Liquid nitrogen and placebo
Placebo Comparator
Liquid nitrogen applied to wart(s) then placebo vehicle afterwards.
干预措施: Liquid nitrogen and topical placebo (Drug)
结局指标
主要结局
Percentage of common warts cleared
时间窗: 12 weeks
Percentage of treated warts cleared with treatment, as measured with dermatoscopic examination, after 12 weeks.
次要结局
未报告次要终点
研究者
研究点 (1)
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