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临床试验/NL-OMON19994
NL-OMON19994已完成不适用

Switching to aflibercept in patients with neovascular age-related macular degeneration not responding to anti-VEGF treatment: a pilot study

Prof. Dr. C.B. HoyngRadboud University Nijmegen Medical Centre, Ophthalmology Department0 个研究点目标入组 20 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
20

研究概览

简要总结

/A

研究设计

研究类型
Interventional

入排标准

入选标准

  • Patients with inadequate response to prior anti-VEGF treatment defined as a persistent central retinal thickness (CRT) of ¡Ý300 ¦Ìm combined with a response of no greater than a reduction of 50 ¦Ìm in CRT on OCT after each previous intravitreal anti-VEGF treatment.
  • - Patients will have received at least 6 anti-VEGF injections within 1 year.

排除标准

  • - Signs of subretinal fibrosis, scarring or geographic atrophy on OCT or FA, involving the center of the macula.
  • - Pigment epithelial detachment with a height of ¡Ý150¦Ìm.

研究者

发起方
Prof. Dr. C.B. HoyngRadboud University Nijmegen Medical Centre, Ophthalmology Department

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