Efficacy and safety of two different doses of vaginal misoprostol for second trimester pregnancy termination in women with previous caesarean section- A Randomised Controlled Study
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Rate of Sucess of abortion in two groups.
研究概览
简要总结
Second trimester termination of pregnancy approximately accounts for 10-15% of abortions being performed worldwide and its incidence is gradually increasing. The challenges faced by an obstetrician increase as the number of previous caesarean increase as there is no consensus on safe method of termination in these cases. We planned this study to find out the efficacious and safe dose of misoprostol for second trimester termination of pregnancy in women with previous caesarean section as there’s higher chance of complications in scarred uterus compared to unscarred uterus
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Singleton pregnancy 2.Previous one or two caesarean section 3.Period of gestation:12 week 0 days to 24 weeks 0 days.
排除标准
- •1.Women with known heart disease 2.Women with low lying placenta.
结局指标
主要结局
Rate of Sucess of abortion in two groups.
时间窗: start and completion of abortion process
Induction abortion interval in hours in both the regimens.
时间窗: start and completion of abortion process
Completeness of Abortion (need for surgical evacuation)- Percentage of cases requiring surgical evacuation or curettage due to retained products of conception in the two groups.
时间窗: start and completion of abortion process
次要结局
- 1.Incidence of side effects related to misoprostol (nausea, vomiting).(2.Amount of blood loss (in ml): Amount of blood loss will be compared in both arms by using the pictorial method.)
研究者
Puneet Kaur
post graduate student