Evaluation of the add-on effect of a traditional nutraceutical supplement ‘Nasaamrutam ’ with Anu Taila Pratimarsha Nasya and Shirishavaleha orally in the management of Vataja Pratishyaya (Allergic rhinitis) - An open-label double-arm randomized controlled clinical trial

Vataja Pratishyaya, described in Ayurveda as a Nasagata Roga, closely correlates with allergic rhinitis, a highly prevalent IgE-mediated inflammatory condition affecting the nasal mucosa. Allergic rhinitis significantly impairs quality of life and has a rising prevalence in India and globally, especially among adolescents. Conventional treatments provide symptomatic relief but are often associated with adverse effects and poor long-term compliance. Hence, there is a growing need for safe, effective, and holistic alternatives. Ayurveda offers well-established therapeutic modalities for Vataja Pratishyaya, including Anu Taila Pratimarsha Nasya for preventive and curative care of nasal disorders and Shirishavaleha for its anti-allergic, anti-inflammatory, and immunomodulatory properties. Previous clinical evidence has shown notable symptomatic improvement with this combination. The present study aims to evaluate the add-on effect of a traditional ready-to-drink nutraceutical supplement, Nasaamrutam, when combined with Anu Taila Pratimarsha Nasya and Shirishavaleha.

Nasaamrutam, formulated with ingredients such as poppy seeds, black pepper, almonds, nutmeg, cardamom, and muskmelon seeds, is traditionally valued for respiratory soothing, immune support, and anti-inflammatory actions. This open-label, double-arm randomized controlled clinical trial seeks to assess whether the addition of Nasaamrutam enhances therapeutic outcomes in Vataja Pratishyaya compared to the standard regimen alone, while also improving palatability and patient compliance with minimal side effects.