Study for Prevention of Cervical Cancer in Spain
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 主要终点
- Prevalence of HPV vaccination and cervical cancer screening among patients diagnosed with cervical cancer in Spain
研究概览
简要总结
The REVIVE study aims to analyze the current status of Human Papillomavirus (HPV) vaccination programs and cervical cancer screening strategies in Spain. Its objective is to gain a comprehensive understanding of the effectiveness of these preventive measures, as well as to identify the main barriers to access and the existing inequalities in care. The study will also examine the impact of misinformation on population engagement and on the overall equity of the prevention system.
Despite significant advances in both vaccination and screening efforts, cervical cancer remains a major public health concern in Spain. In 2024 alone, 2,259 new cases were diagnosed, that incidence has remained relatively stable in recent years, even decades. Mortality rates have also shown little change, with over 600 deaths annually, totaling nearly 10,000 in the last 15 years.
To address this, the study plans to include approximately 200 patients diagnosed with cervical cancer in Spain between 2019 and 2024. It is a retrospective, observational, and non-interventional study. Data will be collected from existing medical records and supplemented with a specific questionnaire administered to the participating patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female patients diagnosed with squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma of the uterine cervix.
- •Diagnosis established between 2019 and 2024.
排除标准
- •Patients aged below 18 years at diagnosis.
- •Diagnosis of other cervical cancer histologies (e.g., neuroendocrine tumors, sarcoma, lymphoma).
- •Patents with significant cognitive impairment precluding informed consent for data utilization, where applicable.
- •Patients with incomplete medical records relevant to the study variables.
结局指标
主要结局
Prevalence of HPV vaccination and cervical cancer screening among patients diagnosed with cervical cancer in Spain
时间窗: 2019-2024
Proportion of individuals diagnosed with cervical cancer who have previously received the HPV vaccine and/or undergone cervical cancer screening prior to their cervical cancer diagnosis. The objective is to assess the effectiveness of national prevention strategies, identify gaps in vaccine and screening coverage, and understand potential barriers to early detection and vaccination.
次要结局
- Percentage of HPV vaccination and screening coverage by region and demographic factors(2019-2024)
- Association between misinformation and socioeconomic factors and the rate of HPV vaccination and screening(2019-2024)
- Reported frequency and nature of barriers to accessing to HPV vaccination and cervical cancer screening(2019-2014)